0 98

Cited 4 times in

Two-year analysis for predicting renal function and contralateral hypertrophy after robot-assisted partial nephrectomy: A three-dimensional segmentation technology study

Authors
 Dae Keun Kim  ;  Yujin Jang  ;  Jaeseon Lee  ;  Helen Hong  ;  Ki Hong Kim  ;  Tae Young Shin  ;  Dae Chul Jung  ;  Young Deuk Choi  ;  Koon Ho Rha 
Citation
 International Journal of Urology, Vol.22(12) : 1105-1111, 2015 
Journal Title
 International Journal of Urology 
ISSN
 0919-8172 
Issue Date
2015
MeSH
Adaptation, Physiological* ; Contrast Media ; Female ; Follow-Up Studies ; Glomerular Filtration Rate ; Humans ; Hypertrophy/diagnostic imaging ; Hypertrophy/physiopathology ; Imaging, Three-Dimensional ; Kidney/diagnostic imaging* ; Kidney/pathology* ; Kidney/physiopathology ; Kidney Neoplasms/pathology* ; Kidney Neoplasms/surgery* ; Male ; Middle Aged ; Nephrectomy*/methods ; Organ Size ; Robotic Surgical Procedures ; Time Factors ; Tomography, X-Ray Computed/methods ; Tumor Burden
Keywords
hypertrophy ; kidney ; nephrectomy ; robotics ; segmentation
Abstract
OBJECTIVES: To analyze long-term changes in both kidneys, and to predict renal function and contralateral hypertrophy after robot-assisted partial nephrectomy. METHODS: A total of 62 patients underwent robot-assisted partial nephrectomy, and renal parenchymal volume was calculated using three-dimensional semi-automatic segmentation technology. Patients were evaluated within 1 month preoperatively, and postoperatively at 6 months, 1 year and continued up to 2-year follow up. Linear regression models were used to identify the factors predicting variables that correlated with estimated glomerular filtration rate changes and contralateral hypertrophy 2 years after robot-assisted partial nephrectomy. RESULTS: The median global estimated glomerular filtration rate changes were -10.4%, -11.9%, and -2.4% at 6 months, 1 and 2 years post-robot-assisted partial nephrectomy, respectively. The ipsilateral kidney median parenchymal volume changes were -24%, -24.4%, and -21% at 6 months, 1 and 2 years post-robot-assisted partial nephrectomy, respectively. The contralateral renal volume changes were 2.3%, 9.6% and 12.9%, respectively. On multivariable linear analysis, preoperative estimated glomerular filtration rate was the best predictive factor for global estimated glomerular filtration rate change on 2 years post-robot-assisted partial nephrectomy (B -0.452; 95% confidence interval -0.84 to -0.14; P = 0.021), whereas the parenchymal volume loss rate (B -0.43; 95% confidence interval -0.89 to -0.15; P = 0.017) and tumor size (B 5.154; 95% confidence interval -0.11 to 9.98; P = 0.041) were the significant predictive factors for the degree of contralateral renal hypertrophy on 2 years post-robot-assisted partial nephrectomy. CONCLUSIONS: Preoperative estimated glomerular filtration rate significantly affects post-robot-assisted partial nephrectomy renal function. Renal mass size and renal parenchyma volume loss correlates with compensatory hypertrophy of the contralateral kidney. Contralateral hypertrophy of the renal parenchyma compensates for the functional loss of the ipsilateral kidney.
Full Text
http://onlinelibrary.wiley.com/doi/10.1111/iju.12913/abstract
DOI
10.1111/iju.12913
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
김기홍(Kim, Ki Hong)
김대근(Kim, Dae Keun)
나군호(Rha, Koon Ho) ORCID logo https://orcid.org/0000-0001-8588-7584
신태영(Shin, Tae Young)
정대철(Jung, Dae Chul) ORCID logo https://orcid.org/0000-0001-5769-5083
최영득(Choi, Young Deuk) ORCID logo https://orcid.org/0000-0002-8545-5797
Export
RIS (EndNote)
XLS (Excel)
XML
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/157109
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse