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Utility of the Montreal Cognitive Assessment (MoCA) and its subset in HIV-associated neurocognitive disorder (HAND) screening

Authors
 Woo Jung Kim  ;  Nam Su Ku  ;  Young-Joon Lee  ;  Jin Young Ahn  ;  Sun Bean Kim  ;  Hye-Won Ahn  ;  Kyung-Wook Hong  ;  Joon Young Song  ;  Hee Jin Cheong  ;  Woo Joo Kim 
Citation
 JOURNAL OF PSYCHOSOMATIC RESEARCH, Vol.80 : 53-57, 2016 
Journal Title
JOURNAL OF PSYCHOSOMATIC RESEARCH
ISSN
 0022-3999 
Issue Date
2016
MeSH
AIDS Dementia Complex/diagnosis* ; AIDS Dementia Complex/psychology* ; Adult ; Attention ; Cognition Disorders/diagnosis* ; Cognition Disorders/etiology ; Cognition Disorders/psychology* ; Executive Function ; Female ; HIV Infections/psychology ; Humans ; Language Tests ; Male ; Mass Screening ; Memory, Short-Term ; Mental Recall ; Middle Aged ; Neuropsychological Tests* ; Reproducibility of Results ; Socioeconomic Factors ; Trail Making Test
Keywords
HIV-associated neurocognitive disorder ; Montreal Cognitive Assessment ; Neuropsychological test ; Screening method
Abstract
OBJECTIVES: The Montreal Cognitive Assessment (MoCA) is a useful screening tool for mild cognitive impairment. We aimed to know whether the full MoCA and subsets of the full test are effective for detecting HIV-associated neurocognitive disorder (HAND).

METHODS: We examined the socio-demographic, clinical, functional, and neuropsychological levels of 194 HIV-infected patients. We compared total scores and scores from each cognitive domain of MoCA between patients with and without HAND. We also examined the utility of subsets of the full test using a few selective domains. The diagnostic accuracies of MoCA and subset composition were evaluated.

RESULTS: The total scores of MoCA (P<0.001) and scores from Trail Making Test-B (P=0.020), attention domain (P=0.005), and immediate (P=0.003) and delayed recall (P=0.002) differed between patients with and without HAND. A subset composed of Trail Making Test-B, rescored serial subtraction, and immediate/delayed recall showed a 69.2% accuracy.

CONCLUSIONS: Our results suggest that the MoCA and its subsets alone are not sufficient in screening for HAND. Further studies will be needed to develop a simpler and easier screening tool for HAND based on this study.
Full Text
http://www.sciencedirect.com/science/article/pii/S0022399915300155
DOI
10.1016/j.jpsychores.2015.11.006
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Ku, Nam Su(구남수) ORCID logo https://orcid.org/0000-0002-9717-4327
Kim, Eosu(김어수) ORCID logo https://orcid.org/0000-0001-9472-9465
Kim, Woo Jung(김우정) ORCID logo https://orcid.org/0000-0002-4963-4819
Kim, June Myung(김준명)
Namkoong, Kee(남궁기) ORCID logo https://orcid.org/0000-0003-1400-8057
Lee, Youngjoon(이영준) ORCID logo https://orcid.org/0000-0002-9602-5186
Choi, Jun Yong(최준용) ORCID logo https://orcid.org/0000-0002-2775-3315
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/151732
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