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고농도의 이산화질소(NO₂)흡입으로 유발된 급성 폐손상 1례

Other Titles
 A Case of Pulmonary Injuny Induced by Accidental Exposure to High Level of Nitrogen Dioxide (NO₂) 
 장진혁  ;  김도연  ;  김영  ;  장윤수  ;  김형중  ;  안철민  ;  김성규  ;  김태훈 
 Journal of the Korean Society of Clinical Toxicology (대한임상독성학회지), Vol.3(1) : 40-44, 2005 
Journal Title
Journal of the Korean Society of Clinical Toxicology(대한임상독성학회지)
Issue Date
Nitrogen dioxide (NO2) ; Acute pulmonary edema
Nitrogen dioxide (NO2) ; Acute pulmonary edema
Nitrogen dioxide(NO_2), which produced during the process of silage, metal etching, explosives, rocket fuels, welding, and by-product of burning of fossil fuels, is one of major components of air pollutant. Accidental exposure of high level of NO_2 produces cough, dyspnea, pulmonary edema which may be delayed 4~12 hours and, in 2~6weeks, bronchiolitis obliterans. We experienced a case of acute pulmonary injuny induced by industrial exposure to high level of NO_2 during repair of NO_2 pipeline in a refinery. A 55-year-old man experienced nausea and severe dyspnea in 6 hours after NO_2 inhalation. Initial blood gas examination revealed severe hypoxemia accompanying increased alveolar-arterial O2 difference. Radiological examination showed diffuse ground glass opacities in both lung fields. Clinical symptoms and laboratory findings, including radiological study and pulmonary function test were improved with conservative treatment using inhaled oxygen and bronchodilator. and there was no evidence of bronchial fibrosis and bronchiolitis obliterance in chest high resolution computed tomography performed 6 weeks after exposure. Here, we report a case of NO_2 induced acute pulmonary injuny with a brief review of the relevant literature.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Youn(김도연)
Kim, Sung Kyu(김성규)
Kim, Tae Hoon(김태훈) ORCID logo https://orcid.org/0000-0003-3598-2529
Kim, Hyung Jung(김형중) ORCID logo https://orcid.org/0000-0003-2498-0683
Ahn, Chul Min(안철민)
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chang, Yoon Soo(장윤수) ORCID logo https://orcid.org/0000-0003-3340-4223
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