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Comparison of Unmonochromatized Synchrotron Radiation and Conventional X-rays in the Imaging of Mammographic Phantom and Human Breast Specimens: A Preliminary Result

Authors
 Haijo Jung  ;  Hee-Joung Kim  ;  Eun-Kyung Kim  ;  Jin-O Hong  ;  Jung Ho Je  ;  Yeukuang Hwu  ;  Wen-Li Tsai  ;  Giorgio Magaritondo  ;  Hyung-Sik Yoo 
Citation
 YONSEI MEDICAL JOURNAL, Vol.46(1) : 95-103, 2005 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2005
MeSH
Breast Diseases/diagnostic imaging* ; Female ; Humans ; Mammography/instrumentation* ; Mammography/methods* ; Phantoms, Imaging* ; Pilot Projects ; Synchrotrons* ; X-Rays
Keywords
Synchrotron radiation ; mammography
Abstract
A simple imaging setup based on the principle of coherence-based contrast X-ray imaging with unmonochromatized synchrotron radiation was used for studying mammographic phantom and human breast specimens. The use of unmonochromatized synchrotron radiation simplifies the instrumentation, decreases the cost and makes the procedure simpler and potentially more suitable for clinical applications. The imaging systems consisted of changeable silicon wafer attenuators, a tungsten slit system, a CdWO4 scintillator screen, a CCD (Charge Coupled Device) camera coupled to optical magnification lenses, and a personal computer. In preliminary studies, a spatial resolution test pattern and glass capillary filled with air bubbles were imaged to evaluate the resOolution characteristics and coherence-based contrast enhancement. Both the spatial resolution and image quality of the proposed system were compared with those of a conventional mammography system in order to establish the characteristic advantages of this approach. The images obtained with the proposed system showed a resolution of at least 25 µm on the test pattern with much better contrast, while the images of the capillary filled with air bubbles revealed coherence-based edge enhancement. This result shows that the coherence-based contrast imaging system, which emphasizes the refraction effect from the edge of materials of different refractive indexes, is applicable to imaging studies in fundamental medicine and biology, although further research works will be required before it can be used for clinical applications.
Files in This Item:
T200500099.pdf Download
DOI
10.3349/ymj.2005.46.1.95
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Kim, Hee Joung(김희중)
Yoo, Hyung Sik(유형식)
Jeong, Hai Jo(정해조)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/147357
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