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Photothermal ablation of cancer cells using self-doped polyaniline nanoparticles

Authors
 Yoochan Hong  ;  Wonseok Cho  ;  Jeonghun Kim  ;  Seungyeon Hwng  ;  Eugene Lee  ;  Dan Heo  ;  Minhee Ku  ;  Jin-Suck Suh  ;  Jaemoon Yang  ;  Jung Hyun Kim 
Citation
 NANOTECHNOLOGY, Vol.27(18) : 185104, 2016 
Journal Title
 NANOTECHNOLOGY 
ISSN
 0957-4484 
Issue Date
2016
MeSH
Aniline Compounds/chemistry* ; Cell Line, Tumor ; Humans ; Hyperthermia, Induced/methods* ; Lauric Acids/pharmacology ; Nanoparticles/chemistry ; Neoplasms/therapy* ; Phototherapy/methods*
Keywords
polyaniline ; nanoparticles ; photothermal ; self-doped
Abstract
Water-stable confined self-doping polyaniline nanocomplexes are successfully fabricated by nano-assembly using lauric acid both as a stabilizer and as a localized dopant. In particular, the colloidal stability of the polyaniline nanocomplexes in neutral pH and the photothermal potential by near-infrared light irradiation are characterized. We demonstrate that confined self-doping polyaniline nanocomplexes as a photothermal nanoagent are preserved in the doped state even at a neutral pH. Finally, confined self-doping polyaniline nanocomplexes aided by lauric acid are successfully applied for the photothermal ablation of cancer cells.
Full Text
http://iopscience.iop.org/article/10.1088/0957-4484/27/18/185104
DOI
10.1088/0957-4484/27/18/185104
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Ku, Min Hee(구민희) ORCID logo https://orcid.org/0000-0002-1674-1474
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Yang, Jae Moon(양재문) ORCID logo https://orcid.org/0000-0001-7365-0395
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/146819
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