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Variability in Interpretation of Ultrasound Elastography and Gray-Scale Ultrasound in Assessing Thyroid Nodules

Authors
 JIEUN KOH  ;  HEE JUNG MOON  ;  JEONG SEON PARK  ;  SOO JIN KIM  ;  HA YAN KIM  ;  EUN-KYUNG KIM  ;  JIN YOUNG KWAK 
Citation
 Ultrasound in Medicine and Biology, Vol.42(1) : 51-59, 2016 
Journal Title
 Ultrasound in Medicine and Biology 
ISSN
 0301-5629 
Issue Date
2016
MeSH
Diagnosis, Differential ; Elasticity Imaging Techniques* ; Female ; Humans ; Male ; Middle Aged ; Observer Variation ; Sensitivity and Specificity ; Thyroid Nodule/diagnostic imaging*
Keywords
Diagnosis ; Elastography ; Inter-observer variability ; Thyroid nodule ; Ultrasound
Abstract
The aim of this study was to validate inter-observer variability for strain ultrasound elastography (USE) and to compare the diagnostic performance of a combination of gray-scale ultrasound (US) and USE with that of gray-scale US. Three observers from different institutions evaluated gray-scale US images and USE video files of 443 cytopathologically proven benign or malignant thyroid nodules over a 3-mo period. Inter-observer variability did not statistically differ between USE using the Asteria criteria and gray-scale US; however, USE using the Rago criteria had the lowest inter-observer agreement (p < 0.043). For all three observers, sensitivity was increased by adding USE to gray-scale US (81.3%-88.3%, 75.4%-85.4%) compared with gray-scale US (70.4%-80.8%). Specificity was decreased by adding USE to gray-scale US (51.7%-59.1%, 59.1%-73.9%) compared with gray-scale US (69.0%-82.8%). USE and gray-scale US had comparable inter-observer variability. However, on addition of USE to gray-scale US, the additional diagnostic yield was limited compared with that of gray-scale US alone.
Full Text
http://www.sciencedirect.com/science/article/pii/S0301562915004871
DOI
10.1016/j.ultrasmedbio.2015.08.005
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
Yonsei Authors
고지은(Koh, Ji Eun)
곽진영(Kwak, Jin Young) ORCID logo https://orcid.org/0000-0002-6212-1495
김은경(Kim, Eun-Kyung) ORCID logo https://orcid.org/0000-0002-3368-5013
김하얀(Kim, Ha Yan)
문희정(Moon, Hee Jung) ORCID logo https://orcid.org/0000-0002-5643-5885
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/145508
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