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Factors Influencing the Background Parenchymal Enhancement in Follow-Up Breast MRI after Adjuvant Endocrine Therapy

 Ji Hyun Youk  ;  Eun Ju Son  ;  Jeong-Ah Kim 
 Investigative Magnetic Resonance Imaging, Vol.19(2) : 99-106, 2015 
Journal Title
 Investigative Magnetic Resonance Imaging 
Issue Date
Purpose : To investigate factors influencing the evaluation of background parenchymal enhancement (BPE) at follow-up breast magnetic resonance imaging (MRI) after adjuvant endocrine therapy. Materials and Methods: One hundred twelve women with breast cancer and MRI of the contralateral unaffected breast before and after endocrine therapy were identified. Two readers in consensus performed blinded side-by-side comparison of BPE (minimal, mild, moderate, and marked) before and after therapy with categorical scales. Age, body mass index, menopausal status, treatment regimen (selective estrogen receptor modulator or aromatase inhibitor), chemotherapy, follow-up duration, BPE at baseline MRI, MRI field strength before and after therapy, and recurrence were analyzed for their influences on decreased BPE. Results : Younger age, premenopausal status, treatment with selective estrogen receptor modulator, MRI field strength, and moderate or marked baseline BPE were significantly associated with decreased BPE. In multivariate analysis, MRI field strength and baseline BPE showed a significant association. Conclusion: MRI field strength and baseline BPE before and after therapy were associated with decreased BPE at post-therapy, follow-up MRI.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
김정아(Kim, Jeong Ah) ORCID logo https://orcid.org/0000-0003-4949-4913
손은주(Son, Eun Ju) ORCID logo https://orcid.org/0000-0002-7895-0335
육지현(Youk, Ji Hyun) ORCID logo https://orcid.org/0000-0002-7787-780X
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