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Factors Influencing the Background Parenchymal Enhancement in Follow-Up Breast MRI after Adjuvant Endocrine Therapy

Authors
 Ji Hyun Youk ; Eun Ju Son ; Jeong-Ah Kim 
Citation
 Investigative Magnetic Resonance Imaging, Vol.19(2) : 99~106, 2015 
Journal Title
 Investigative Magnetic Resonance Imaging 
ISSN
 2384-1095 
Issue Date
2015
Abstract
Purpose : To investigate factors influencing the evaluation of background parenchymal enhancement (BPE) at follow-up breast magnetic resonance imaging (MRI) after adjuvant endocrine therapy. Materials and Methods: One hundred twelve women with breast cancer and MRI of the contralateral unaffected breast before and after endocrine therapy were identified. Two readers in consensus performed blinded side-by-side comparison of BPE (minimal, mild, moderate, and marked) before and after therapy with categorical scales. Age, body mass index, menopausal status, treatment regimen (selective estrogen receptor modulator or aromatase inhibitor), chemotherapy, follow-up duration, BPE at baseline MRI, MRI field strength before and after therapy, and recurrence were analyzed for their influences on decreased BPE. Results : Younger age, premenopausal status, treatment with selective estrogen receptor modulator, MRI field strength, and moderate or marked baseline BPE were significantly associated with decreased BPE. In multivariate analysis, MRI field strength and baseline BPE showed a significant association. Conclusion: MRI field strength and baseline BPE before and after therapy were associated with decreased BPE at post-therapy, follow-up MRI.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/140963
DOI
10.13104/imri.2015.19.2.99
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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