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The Role of Orexin in Post- Stroke; Emphasizing on Inflammation, Cognitive decline, Depression following Stroke.

DC FieldValueLanguage
dc.contributor.author김어수-
dc.contributor.author김철훈-
dc.contributor.author송주현-
dc.contributor.author송호택-
dc.contributor.author이종은-
dc.date.accessioned2016-02-04T11:04:18Z-
dc.date.available2016-02-04T11:04:18Z-
dc.date.issued2015-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/139599-
dc.description.abstractIschemic stroke results in diverse pathophysiologies, including cerebral inflammation, neuronal loss, cognitive dysfunction, and depression. Studies aimed at identifying therapeutic solutions to alleviate these outcomes are important due to the increase in the number of stroke patients annually. Recently, many studies have reported that orexin, commonly known as a neuropeptide regulator of sleep/wakefulness and appetite, is associated with neuronal cell apoptosis, memory function, and depressive symptoms. Here, we briefly summarize recent studies regarding the role and future perspectives of orexin in post-ischemic stroke. This review advances our understanding of the role of orexin in post-stroke pathologies, focusing on its possible function as a therapeutic regulator in the post-ischemic brain. Ultimately, we suggest the clinical potential of orexin to regulate post-stroke pathologies.-
dc.description.statementOfResponsibilityopen-
dc.format.extent16-
dc.relation.isPartOfMOLECULAR BRAIN-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHCognition Disorders/etiology*-
dc.subject.MESHCognition Disorders/metabolism-
dc.subject.MESHDepression/etiology*-
dc.subject.MESHDepression/metabolism-
dc.subject.MESHHumans-
dc.subject.MESHInflammation/etiology*-
dc.subject.MESHInflammation/metabolism-
dc.subject.MESHModels, Biological-
dc.subject.MESHOrexins/metabolism*-
dc.subject.MESHStroke/complications*-
dc.subject.MESHStroke/metabolism-
dc.titleThe Role of Orexin in Post- Stroke; Emphasizing on Inflammation, Cognitive decline, Depression following Stroke.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiology (영상의학)-
dc.contributor.googleauthorJuhyun Song-
dc.contributor.googleauthorEosu Kim-
dc.contributor.googleauthorChul-Hoon Kim-
dc.contributor.googleauthorHo-Taek Song-
dc.contributor.googleauthorJong Eun Lee-
dc.identifier.doi10.1186/s13041-015-0106-1-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00686-
dc.contributor.localIdA01057-
dc.contributor.localIdA02063-
dc.contributor.localIdA02080-
dc.contributor.localIdA03146-
dc.relation.journalcodeJ02251-
dc.identifier.eissn1756-6606-
dc.identifier.pmid25884812-
dc.subject.keywordPost-stroke-
dc.subject.keywordOrexin-
dc.subject.keywordInflammation-
dc.subject.keywordCognitive dysfunction-
dc.subject.keywordDepression-
dc.contributor.alternativeNameKim, Eo Su-
dc.contributor.alternativeNameKim, Chul Hoon-
dc.contributor.alternativeNameSong, Ju Hyun-
dc.contributor.alternativeNameSong, Ho Taek-
dc.contributor.alternativeNameLee, Jong Eun-
dc.contributor.affiliatedAuthorKim, Eo Su-
dc.contributor.affiliatedAuthorKim, Chul Hoon-
dc.contributor.affiliatedAuthorSong, Ju Hyun-
dc.contributor.affiliatedAuthorSong, Ho Taek-
dc.contributor.affiliatedAuthorLee, Jong Eun-
dc.rights.accessRightsnot available-
dc.citation.volume8-
dc.citation.startPage16-
dc.identifier.bibliographicCitationMOLECULAR BRAIN, Vol.8 : 16, 2015-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Anatomy (해부학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers

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