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Effect of calcium phosphate glass scaffold with chitosan membrane on the healing of alveolar bone in 1 wall intrabony defect in the beagle dogs

Authors
 D.H. Min  ;  M.J. Kim  ;  Chong Kwan Kim  ;  Kyoung Nam Kim  ;  Seong Ho Choi  ;  Yong Keun Lee  ;  C.S. Kim  ;  J.H. Yun 
Citation
 Key Engineering Materials, Vol.284~286 : 851-854, 2005 
Journal Title
 Key Engineering Materials 
ISSN
 1013-9826 
Issue Date
2005
MeSH
Beagle Dog ; Bone ; Calcium Phosphate Glass ; Chitosan Nonwoven Membrane
Keywords
Beagle Dog ; Bone ; Calcium Phosphate Glass ; Chitosan Nonwoven Membrane
Abstract
This study evaluated periodontal repair and biomaterial reaction following implantation of a newly fabricated calcium phosphate block bone with chitosan membrane on the regeneration of 1-wall intrabony defects in the beagle dogs. The surgical control group received a flap operation only, while the experimental group I was treated with a chitosan nonwoven membrane only and the experimental group II was treated with a chitosan nonwoven membrane and a calcium phosphate block bone. The subjects were sacrificed 12 weeks after surgery and a comparative histometric analysis was done. No root resorption or ankylosis were observed in the experimental group. Mann-Whitney U test showed that the experimental group II produced statistically significant higher gain in connective tissue adhesion, new cementum regeneration and new bone formation. Based on histological results, the calcium phosphate block bone successfully functioned as a osteoconductive scaffold for invading cells of host.
Full Text
http://www.scientific.net/KEM.284-286.851
DOI
10.4028/www.scientific.net/KEM.284-286.851
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyoung Nam(김경남)
Kim, Chong Kwan(김종관)
Kim, Chang Sung(김창성) ORCID logo https://orcid.org/0000-0003-3902-1071
Yun, Jeong Ho(윤정호)
Lee, Yong Keun(이용근)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/114831
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