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Effect of calcium phosphate glass on compressive strength of macroporous hydroxyapatite scaffold

 Yeon Ung Kim  ;  Min Chul Kim  ;  Yong Keun Lee  ;  Racquel Z. LeGeros  ;  Chong Kwan Kim  ;  Seong Ho Choi  ;  Kwang Mahn Kim  ;  Kyoung Nam Kim 
 Key Engineering Materials, Vol.284-286 : 313-316, 2005 
Journal Title
Key Engineering Materials
Issue Date
Bone ; Calcium Phosphate Glass ; Compressive Strength ; Hydroxyapatite (HAP) ; Scaffold
Bone ; Calcium Phosphate Glass ; Compressive Strength ; Hydroxyapatite (HAP) ; Scaffold
This study presents the manufacture of macroporous hydroxyapatite scaffolds with a small amount of calcium phosphate glass powder as sintering additives. Hydroxyapatite slurry was prepared by suspending the hydroxyapatite and glass powder in water. Polyurethane sponge was used to produce highly macroporous scaffolds. The rheological characteristic of the slurry was measured to identify the effect of adding calcium phosphate glass powder into hydroxyapatite slurry. Sintered scaffolds could be repeatedly coated to improve mechanical properties. Scaffolds prepared by single and double replication cycle process were characterized by density, porosity and compressive strength measurements by increasing amount of the calcium phosphate glass powder to the hydroxyapatite slurry, viscosity by increased more than same amount of pure hydroxyapatite, and the capillary force was similar to pure hydroxyapatite slurry. The compressive strength of the macroporous hydroxyxapatite scaffold containing the calcium phosphate glass powder showed higher value than that of pure hydroxyapatite at single replication cycle. SEM demonstrated that the microstructure of the scaffold became denser with the introduction of the calcium phosphate glass powder. The pore struts were thicker as replication cycle was increased.
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2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyoung Nam(김경남)
Kim, Kwang Mahn(김광만) ORCID logo https://orcid.org/0000-0002-5235-0294
Kim, Min Chul(김민철)
Kim, Chong Kwan(김종관)
Lee, Yong Keun(이용근)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
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