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치주조직 재생을 위한 칼슘 포스페이트 글라스 분말이 백서 두개골 결손부의 골조직 재생에 미치는 영향

Other Titles
 Effect of Calcium Phosphate Glass Powder for Periodontal Regeneration onBone Formation of Calvarial Defects in Sprague-Dawley Rats 
Authors
 이용근  ;  문현주  ;  최성호  ;  김경남  ;  김광만  ;  이상배 
Citation
 Journal of the Korean Research Society for Dental Materials (대한치과기재학회지), Vol.30(2) : 153-161, 2003 
Journal Title
Journal of the Korean Research Society for Dental Materials(대한치과기재학회지)
ISSN
 1225-1631 
Issue Date
2003
MeSH
bone regeneration ; calcium phosphate ; calvarial defect ; rat
Keywords
bone regeneration ; calcium phosphate ; calvarial defect ; rat
Abstract
The treatment of the bone defects resulting from trauma, neoplasm, surgery, or infection is one of the major concern in dentistry. The major goal is the functional, esthetical regeneration of supporting structures already destructed by disease.
Transplantation technique have been used to provide a scaffold for bone regeneration, to augment bony defects resulting from trauma or surgery, to restore bone loss caused by dental disease, to prevent the collapse the alveolar ridge in recent
extraction sites, to replace bone loss by periodontal disease, to augment the alveolar ridge in implant surgery. There are autogeneous, allogenic, xenogenic and alloplastic bone-grafts in transplantation. Among the alloplastic bone-graft materials,
calcium phosphates have been received the most attention. In this study, the critical size defects were surgically produced in the calvarial bone of Sprague-Dawley rats using the 8 mm trephine bur. Calcium phosphate glass powders with mean diameter 400
micro m transplanted onto the produced defects in the experimental group, while sutured without grafting anything in the control group. Histomorphometric as well as radiodensitometric analyses were performed after sacrifice at 2, 4 and 8 weeks following
operation. The prepared calcium phosphate glass powder with average size 400 micro m in CaO-CaF(2)-P(2)O(5)-MgO-Al(2)O(3) promoted new bone formation in the calvarial defects in the Sprague-Dawley rats. New bone was formed in the upper side of the
defects as well as the defect margin and dura mater. Experimental group always exhibited higher values in the length, area and density of the newly formed bone than that of the control group. There were significant differences between the experimental
and the control groups, except the density after 4 weeks (p<0.05).
Full Text
http://www.dbpia.co.kr/Article/3402069
DOI
OAK-2003-00074
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kwang Mahn(김광만) ORCID logo https://orcid.org/0000-0002-5235-0294
Lee, Yong Keun(이용근)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/113234
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