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Pregnancy-associated breast disease: Radiologic features and diagnostic dilemmas

 Eun Ju Son  ;  Ki Keun Oh  ;  Eun Kyung Kim 
 YONSEI MEDICAL JOURNAL, Vol.47(1) : 34-42, 2006 
Journal Title
Issue Date
Adult ; Biopsy ; Breast/pathology ; Breast/surgery ; Breast Diseases/diagnostic imaging* ; Breast Diseases/pathology ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Female ; Humans ; Mammography* ; Pregnancy ; Pregnancy Complications/diagnosis ; Pregnancy Complications/diagnostic imaging* ; Pregnancy Complications/surgery ; Ultrasonography, Mammary
Breast diseases ; pregnancy ; ultrasonography ; breast radiography
In this paper, we evaluate the radiological features of pregnancy-associated breast lesions and discuss the difficulties in diagnosis by imaging. We selected patients who were diagnosed with pregnancy-associated breast lesions during the previous 5 years. All patients complained of palpable lesions in the breast and underwent ultrasonographic (US) examination, the first choice for examination of pregnancy-related breast lesions. Any suspicious lesions found by the US were recommended for a US-guided core biopsy, US-guided fine needle aspiration (FNA), or surgery. Various breast lesions were detected during pregnancy and lactation, including breast cancer, mastitis and abscesses, lactating adenoma, galactoceles, lobular hyperplasia, and fibroadenomas. The imaging features of pregnancy-associated breast lesions did not differ from the features of non-pregnancy-associated breast lesions; however, some pregnancy-associated benign lesions had suspicious sonographic features. A US-guided core biopsy was necessary for differentiating benign from malignant. In patients with breast cancer, the cancer was often advanced at the time of diagnosis. In conclusion, various pregnancy-related breast lesions were detected and the imaging of these lesions had variable findings. Breast ultrasound could be an excellent imaging modality for diagnosis and differentiation between benign and malignant lesions. However, when the imaging results are suspicious, a biopsy should be performed to obtain a pathologic diagnosis.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Son, Eun Ju(손은주) ORCID logo https://orcid.org/0000-0002-7895-0335
Oh, Ki Keun(오기근)
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