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Saline flush effect for enhancement of aorta and coronary arteries at multidetector CT coronary angiography

Authors
 Dae Jung Kim  ;  Tae Hoon Kim  ;  Sang Jin Kim  ;  Dong Phil Kim  ;  Chi Suk Oh  ;  Young Hoon Ryu  ;  Young Jin Kim  ;  Byoung Wook Choi 
Citation
 RADIOLOGY, Vol.246(1) : 110-115, 2008 
Journal Title
 RADIOLOGY 
ISSN
 0033-8419 
Issue Date
2008
MeSH
Adult ; Aged ; Aged, 80 and over ; Aortography/methods* ; Contrast Media/administration & dosage* ; Coronary Angiography/methods* ; Female ; Humans ; Injections, Intravenous ; Male ; Middle Aged ; Prospective Studies ; Sodium Chloride/administration & dosage* ; Tomography, X-Ray Computed*
Keywords
Adult ; Aged ; Aged, 80 and over ; Aortography/methods* ; Contrast Media/administration & dosage* ; Coronary Angiography/methods* ; Female ; Humans ; Injections, Intravenous ; Male ; Middle Aged ; Prospective Studies ; Sodium Chloride/administration & dosage* ; Tomography, X-Ray Computed*
Abstract
PURPOSE: To prospectively investigate the effect of the injection rate of a saline solution as a bolus chaser for the enhancement of the aorta and coronary arteries at multidetector computed tomographic (CT) coronary angiography. MATERIALS AND METHODS: Institutional review board approved this study, and all patients gave informed consent. One hundred consecutive patients (59 men, 41 women; mean age, 58 years +/- 11 [standard deviation]) underwent 64-section CT coronary angiography for coronary artery disease. They were divided into five groups (each group, n = 20) according to the injection rate of saline solution (3, 4, 5, 6, and 7 mL/sec). Iodinated contrast medium (60 mL) was injected intravenously at a rate of 4 mL/sec, followed by 60 mL saline solution administered intravenously at a rate of 3-7 mL/sec, depending on the groups. Attenuation values of the aortic root, right coronary artery, left anterior descending artery, and left circumflex artery were measured. Analysis of variance with the Scheffé method was used to evaluate statistical significance of the differences in attenuation according to the injection rate of saline solution. RESULTS: The degree of contrast enhancement was affected by the injection rate of saline solution, and the attenuation values were higher as the injection rate increased up to 4-5 mL/sec (P < .05). The values plateaued at rates over 5 mL/sec in the aorta and over 4 mL/sec in the coronary arteries. CONCLUSION: An injection rate of 4-5 mL/sec as a saline solution chaser is optimal for achieving maximum attenuation values of the aorta or coronary arteries by using 64-section CT with 60 mL contrast material
Full Text
http://pubs.rsna.org/doi/abs/10.1148/radiol.2453061953
DOI
10.1148/radiol.2453061953
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Jin(김상진)
Kim, Young Jin(김영진) ORCID logo https://orcid.org/0000-0002-6235-6550
Kim, Tae Hoon(김태훈) ORCID logo https://orcid.org/0000-0003-3598-2529
Ryu, Young Hoon(유영훈) ORCID logo https://orcid.org/0000-0002-9000-5563
Choi, Byoung Wook(최병욱) ORCID logo https://orcid.org/0000-0002-8873-5444
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/107044
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