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Extrathyroid extension of well-differentiated papillary thyroid microcarcinoma on US.

Authors
 Jin Young Kwak  ;  Eun-Kyung Kim  ;  Ji Hyun Youk  ;  Min Jung Kim  ;  Eun Ju Son  ;  Seon Hyeong Choi  ;  Ki Keun Oh 
Citation
 THYROID, Vol.18(6) : 609-614, 2008 
Journal Title
 THYROID 
ISSN
 1050-7256 
Issue Date
2008
MeSH
Adult ; Aged ; Aged, 80 and over ; Carcinoma, Papillary/diagnosis ; Carcinoma, Papillary/diagnostic imaging* ; Carcinoma, Papillary/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Odds Ratio ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Sensitivity and Specificity ; Thyroid Gland/diagnostic imaging* ; Thyroid Gland/pathology ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/diagnostic imaging* ; Thyroid Neoplasms/pathology ; Ultrasonography
Keywords
Adult ; Aged ; Aged, 80 and over ; Carcinoma, Papillary/diagnosis ; Carcinoma, Papillary/diagnostic imaging* ; Carcinoma, Papillary/pathology ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Invasiveness ; Odds Ratio ; Predictive Value of Tests ; Prognosis ; Retrospective Studies ; Sensitivity and Specificity ; Thyroid Gland/diagnostic imaging* ; Thyroid Gland/pathology ; Thyroid Neoplasms/diagnosis ; Thyroid Neoplasms/diagnostic imaging* ; Thyroid Neoplasms/pathology ; Ultrasonography
Abstract
BACKGROUND: Extrathyroidal extension is an important factor to determine the extent of thyroid surgery. The aim of the present study was to evaluate the usefulness of high-resolution ultrasound (US) for predicting the extrathyroidal extension of papillary thyroid microcarcinoma (PTMC). METHODS: This study included a total of 221 PTMCs in 181 patients. PTMC was defined as thyroid papillary carcinoma equal or less than 1 cm in size. The US findings, such as contact and disruption of thyroid capsule, were evaluated to predict the extrathyroidal extension of thyroid carcinoma. We calculated the diagnostic accuracy and odds ratio for each US finding. RESULTS: Of the 221 PTMCs, extrathyroidal extension was present in 89 (40.3%) based on pathologic results. The mean size was not significantly different between PTMCs with and without extrathyroidal extension (p = 0.527). When the degree of contact was high, extrathyroidal extension of the thyroid cancer was high (p < 0.0001). Considering the odds ratio, Az value, and positive predictive value of each US finding, more than 25% contact with the adjacent capsule is the most accurate measurement for predicting extrathyroidal extension. CONCLUSIONS: This study suggests that the presence and degree of contact between a PTMC and the adjacent capsule as found on preoperative US can provide an useful predictive information about an extrathyroidal extension.
Full Text
http://online.liebertpub.com/doi/abs/10.1089/thy.2007.0345
DOI
10.1089=thy.2007.0345
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Jin Young(곽진영) ORCID logo https://orcid.org/0000-0002-6212-1495
Kim, Min Jung(김민정) ORCID logo https://orcid.org/0000-0003-4949-1237
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Son, Eun Ju(손은주) ORCID logo https://orcid.org/0000-0002-7895-0335
Oh, Ki Keun(오기근)
Youk, Ji Hyun(육지현) ORCID logo https://orcid.org/0000-0002-7787-780X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/106226
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