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구축된 간암 발생 예측 모형의 개선방안에 관한 연구

Other Titles
 A study on the updating of prediction model for the development of hepatoma 
Authors
 이혜선  ;  명성민  ;  김도영  ;  한광협  ;  송기준 
Citation
 Journal of the Korea Society of Health Informatics and Statistics, Vol.34(2) : 139-152, 2009 
Journal Title
 Journal of the Korea Society of Health Informatics and Statistics (한국보건정보통계학회지) 
ISSN
 1226-9476 
Issue Date
2009
Keywords
prediction model ; update method ; re-calibration ; shrinkage ; intercept ; slope
Abstract
Objectives: The statistical prediction models are useful to establishing diagnostic and treatment rule in clinical area. So, there is an increasing interest in building a precise model to predict the probability of diseases for individual patient. In doing that, it is important to reflect the patient`s changeable characteristics for improvement of predictive power. In this paper, we studied the methods for the updating of prediction model that add the information of new patients to the existing model. Methods: To update the prediction model, we used an established model including 7 risk factors such as diagnostic type, hepatitic virus type, age, sex, -FP, ALT, and drinking history and did the re-calibration and shrinkage of intercept and slope of existing one. Results: we considered 4 updating methods, that is, the first one is to use existing model as it is and the second one is to re-calibrate the overall intercept. Also the third one is to re-calibrate overall intercept and slope and the last one is to re-calibrate and shrink overall intercept, and individual slope. Conclusions: Updating methods contain old and new informations. And the model updating method by using many data can be improved predictive power. Especially, the last updating method was found to be the most accurate and useful one
Files in This Item:
T200905886.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Medical Engineering (의학공학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Young(김도영)
Song, Ki Jun(송기준) ORCID logo https://orcid.org/0000-0003-2505-4112
Lee, Hye Sun(이혜선) ORCID logo https://orcid.org/0000-0001-6328-6948
Han, Kwang-Hyub(한광협) ORCID logo https://orcid.org/0000-0003-3960-6539
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/105962
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