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A case of suspected isotretinoin-induced malformation in a baby of a mother who became pregnant one month after discontinuation of the drug.

Authors
 Soon Min Lee  ;  He Min Kim  ;  Jun Seok Lee  ;  Choon Sik Yoon  ;  Min Soo Park  ;  Kook In Park  ;  Ran Namgung  ;  Chul Lee 
Citation
 YONSEI MEDICAL JOURNAL, Vol.50(3) : 445-447, 2009 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2009
MeSH
Abnormalities, Drug-Induced/diagnosis* ; Abnormalities, Drug-Induced/etiology* ; Abnormalities, Drug-Induced/pathology ; Adult ; Female ; Humans ; Infant, Newborn ; Isotretinoin/adverse effects* ; Male ; Pregnancy ; Prenatal Exposure Delayed Effects*
Keywords
Isotretinoin ; malformation
Abstract
Isotretinoin is a known human teratogen that can cause multiple malformations. At present, women who conceive one cycle after discontinuing isotretinoin are told that their teratogenic risk is not higher than baseline. We present a case of both-ear malformation in a newborn whose mother had taken isotretinoin for 2 years until one month prior to the time when she became pregnant. We suggest that further studies of pharmacokinetics and malformation of isotretinoin are needed
Files in This Item:
T200902962.pdf Download
DOI
10.3349/ymj.2009.50.3.445
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Namgung, Ran(남궁란) ORCID logo https://orcid.org/0000-0001-7182-9535
Park, Kook In(박국인) ORCID logo https://orcid.org/0000-0001-8499-9293
Park, Min Soo(박민수) ORCID logo https://orcid.org/0000-0002-4395-9938
Yoon, Choon Sik(윤춘식) ORCID logo https://orcid.org/0000-0003-2010-6710
Lee, Soon Min(이순민) ORCID logo https://orcid.org/0000-0003-0174-1065
Lee, Chul(이철)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/104516
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