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Effect of clinical information on diagnostic performance in breast sonography

 Song-Ee Baek  ;  Min Jung Kim  ;  Eun-Kyung Kim  ;  Ji Hyun Youk  ;  Hye-Jeong Lee  ;  MD, Eun Ju Son 
 Journal of Ultrasound in Medicine, Vol.28(10) : 1349-1356, 2009 
Journal Title
 Journal of Ultrasound in Medicine 
Issue Date
OBJECTIVE: The purpose of this study was to assess whether the clinical information (CI) of patients affects the degree of suspicion for malignancy by radiologists performing breast sonography. METHODS: We included 150 breast lesions in 144 patients who underwent breast sonography and sonographically guided core needle biopsy. A pathologic diagnosis was available for all 150 breast lesions: 78 (52%) were malignant, and 72 (48%) were benign. Three radiologists retrospectively reviewed the sonograms of all lesions twice at 8-week intervals first without any CI for the patients (first review) and then with CI such as patient age, palpability, and personal history of risk factors for breast cancer (second review). The reviewers categorized the final assessment according to the American College of Radiology Breast Imaging Reporting and Data System. We compared diagnostic performance such as sensitivity and specificity and the degree of suspicion for malignancy between the image reviews with and without CI. RESULTS: In the second review, sensitivity was improved in all 3 reviewers (94.0 to 99.2%; P < .05), and specificity was decreased (39.8 to 30.8%; P = .04). There was a significant increase of suspicion for malignancy with the patients' CI (P < .05). CONCLUSIONS: Clinical information about a patient's breast cancer history and clinical presentation with a palpable mass can increase the suspicion for malignancy on sonography and the sensitivity of sonographic interpretation.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실)
Yonsei Authors
김민정(Kim, Min Jung) ORCID logo https://orcid.org/0000-0003-4949-1237
김은경(Kim, Eun-Kyung) ORCID logo https://orcid.org/0000-0002-3368-5013
백송이(Baek, Song Ee) ORCID logo https://orcid.org/0000-0001-8146-2570
손은주(Son, Eun Ju)
육지현(Youk, Ji Hyun) ORCID logo https://orcid.org/0000-0002-7787-780X
이혜정(Lee, Hye Jeong) ORCID logo https://orcid.org/0000-0003-4349-9174
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