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Characterization of microcalcification: can digital monitor zooming replace magnification mammography in full-field digital mammography?

 Min Jung Kim  ;  Eun-Kyung Kim  ;  Jin Young Kwak  ;  Eun Ju Son  ;  Ji Hyun Youk  ;  Seon Hyeong Choi  ;  Mooyoung Han  ;  Ki Keun Oh 
 EUROPEAN RADIOLOGY, Vol.19(2) : 310-317, 2009 
Journal Title
Issue Date
Biopsy ; Breast Diseases/diagnostic imaging ; Breast Diseases/pathology ; Breast Neoplasms/diagnosis* ; Calcinosis/diagnosis* ; Calcinosis/diagnostic imaging* ; Early Detection of Cancer ; Humans ; Image Processing, Computer-Assisted ; Mammography/methods* ; Medical Oncology/methods ; Models, Statistical ; ROC Curve ; Radiology/methods ; Reproducibility of Results ; Sensitivity and Specificity
Mammography ; Microcalcifications ; Magnification ; Digital mammography ; Zooming
The aim of this study was to compare the diagnostic accuracy and image quality of microcalcifications in zoomed digital contact mammography with digital magnification mammography. Three radiologists with different levels of experience in mammography reviewed 120 microcalcification clusters in 111 patients with a full-field digital mammography system relying on digital magnification mammogram (MAG) images and zoomed images from contact mammography (ZOOM) using commercially available zooming systems on monitors. Each radiologist estimated the probability of malignancy and rated the image quality and confidence rate. Performance was evaluated by sensitivity, specificity, positive predictive value, negative predictive value, and receiver operating characteristic (ROC) analysis. All three radiologists rated MAG images higher than ZOOM images for sensitivity with statistical significance (average value, 92% vs. 87%, P<0.05) and performance by ROC analysis improved with MAG imaging. The confidence rate for diagnosis decision and the assessment of lesion characteristics were also better in MAG images than in ZOOM images with statistical significance (P<0.0001). Digital magnification mammography can enhance diagnostic performance when characterizing microcalcifications. Images zoomed from digital contact mammography cannot serve as an alternative to direct magnification digital mammography
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Jin Young(곽진영) ORCID logo https://orcid.org/0000-0002-6212-1495
Kim, Min Jung(김민정) ORCID logo https://orcid.org/0000-0003-4949-1237
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Son, Eun Ju(손은주) ORCID logo https://orcid.org/0000-0002-7895-0335
Oh, Ki Keun(오기근)
Youk, Ji Hyun(육지현) ORCID logo https://orcid.org/0000-0002-7787-780X
Choi, Seon Hyeong(최선형)
Han, Moo Young(한무영)
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