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Comparison of two different injection rates of gadoxetic acid for arterial phase MRI of the liver

Authors
 Sang-Hoon Chung  ;  Myeong-Jin Kim  ;  Jin-Young Choi  ;  Hye-Suk Hong 
Citation
 JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol.31(2) : 365-372, 2010 
Journal Title
JOURNAL OF MAGNETIC RESONANCE IMAGING
ISSN
 1053-1807 
Issue Date
2010
MeSH
Adult ; Aged ; Aged, 80 and over ; Contrast Media/administration & dosage ; Female ; Gadolinium DTPA/administration & dosage* ; Humans ; Image Enhancement/methods* ; Injections, Intra-Arterial ; Liver/pathology* ; Liver Neoplasms/pathology* ; Magnetic Resonance Imaging/methods* ; Middle Aged ; Reproducibility of Results ; Sensitivity and Specificity
Keywords
InjIection rate ; Gadoxetic acid ; Hepatic dynamic MR ; hepatocellular carcinoma ; contrast material
Abstract
PURPOSE: To compare two different injection rates for gadoxetic acid-enhanced hepatic arterial phase images on hepatic dynamic MRI.

MATERIALS AND METHODS: Hepatic arterial phase images were obtained after an intravenous bolus injection of gadoxetic acid at a rate of 1 mL/second in 62 patients and 2 mL/second in 64 patients on a 3 Tesla MR scanner using a test-bolus injection method. The signal-to-noise ratios (SNR) of the liver, portal vein, hepatic vein, aorta, spleen and pancreas were measured. The contrast-to-noise ratio (CNR) of hypervascular hepatic tumors was calculated. Two radiologists independently scored items to evaluate image quality of hepatic arterial phase and detected hypervascular hepatocellular carcinoma (HCC).

RESULTS: The SNR of the aorta on the arterial phase images was significantly higher in the 1 mL/second group (235.43 +/- 82.59) than in the 2 mL/second group (190.94 +/- 96.90, P < 0.05). The SNRs of the liver, spleen and pancreas, the CNRs of hypervascular hepatic tumors, the detection rate of hypervascular HCC and subjective ratings for the optimal arterial enhancement were comparable between the two groups.

CONCLUSION: Injection rates of 2 mL/second and 1 mL/second provided comparable image qualities on arterial phase images of hepatic dynamic MRI using gadoxetic acid.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/jmri.22057/abstract
DOI
10.1002/jmri.22057
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Choi, Jin Young(최진영) ORCID logo https://orcid.org/0000-0002-9025-6274
Hong, Hye Suk(홍혜숙) ORCID logo https://orcid.org/0000-0001-7398-2517
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/100516
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