Browsing by Yonsei Author : Yu, Je Wook

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Yu, Je Wook [유제욱]
Department :
College of Medicine (의과대학) - Dept. of Microbiology (미생물학교실)
Scopus ID :
Scopus (22935887000)

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Issue DateTitleJournal Title
2022Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model EBIOMEDICINE
2022Design and synthesis of an N-benzyl 5-(4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitorBIOORGANIC & MEDICINAL CHEMISTRY LETTERS
2022Differential Regional Vulnerability of the Brain to Mild Neuroinflammation Induced by Systemic LPS Treatment in Mice JOURNAL OF INFLAMMATION RESEARCH
2022Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21 FRONTIERS IN IMMUNOLOGY
2022PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis CELL DEATH & DISEASE
2021Intracellular NAD + Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation FRONTIERS IN IMMUNOLOGY
2021Antimicrobial Peptide LL-37 Drives Rosacea-Like Skin Inflammation in an NLRP3-Dependent MannerJOURNAL OF INVESTIGATIVE DERMATOLOGY
2021Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu FRONTIERS IN IMMUNOLOGY
2021Distinct Features of Brain-Resident Macrophages: Microglia and Non-Parenchymal Brain Macrophages MOLECULES AND CELLS
2021SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models EMBO MOLECULAR MEDICINE
2020Antiviral efficacy of orally delivered neoagarohexaose, a nonconventional TLR4 agonist, against norovirus infection in miceBIOMATERIALS
2020Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling FRONTIERS IN IMMUNOLOGY
2020ATP-P2X7-Induced Inflammasome Activation Contributes to Melanocyte Death and CD8 + T-Cell Trafficking to the Skin in VitiligoJOURNAL OF INVESTIGATIVE DERMATOLOGY
2020SGLT2 Inhibition Modulates NLRP3 Inflammasome Activity via Ketones and Insulin in Diabetes With Cardiovascular Disease NATURE COMMUNICATIONS
2020Non-invasive in vivo imaging of caspase-1 activation enables rapid and spatiotemporal detection of acute and chronic inflammatory disorders BIOMATERIALS
2019Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner IMMUNE NETWORK
2019Proteomics-based functional studies reveal that galectin-3 plays a protective role in the pathogenesis of intestinal Behçet's disease Scientific Reports
2019Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation FRONTIERS IN IMMUNOLOGY
2019Brefeldin A-sensitive ER-Golgi vesicle trafficking contributes to NLRP3-dependent caspase-1 activationFASEB JOURNAL
2019MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegenerationCELL DEATH AND DIFFERENTIATION
2018Palmitate and minimally-modified low-density lipoprotein cooperatively promote inflammatory responses in macrophages PLOS ONE
2018Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1beta in Macrophages JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY
2017Advanced glycation end products impair NLRP3 inflammasome-mediated innate immune responses in macrophagesJOURNAL OF BIOLOGICAL CHEMISTRY
2017NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
2017Immunomodulatory/anti-inflammatory effect of ZOE-based dental materialsDENTAL MATERIALS
2017Bacterial Secretant from Pseudomonas aeruginosa Dampens Inflammasome Activation in a Quorum Sensing-Dependent Manner FRONTIERS IN IMMUNOLOGY
2016Mitochondria and the NLRP3 inflammasome: physiological and pathological relevanceARCHIVES OF PHARMACAL RESEARCH
201625-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome NATURE COMMUNICATIONS
2016Inflammasome activation by cell volume regulation and inflammation-associated hyponatremia: A vicious cycleMEDICAL HYPOTHESES
2016Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2015Histone deacetylase 6 negatively regulates NLRP3 inflammasome activationBIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
2015Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation JOURNAL OF BIOLOGICAL CHEMISTRY
2015Defective mitochondrial fission augments NLRP3 inflammasome activation SCIENTIFIC REPORTS
2015Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4IMMUNOLOGY AND CELL BIOLOGY
2013Cobalt Chloride-induced Hypoxia Ameliorates NLRP3-Mediated Caspase-1 Activation in Mixed Glial Cultures IMMUNE NETWORK
2013The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome ActivityJOURNAL OF IMMUNOLOGY
2013Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome JOURNAL OF BIOLOGICAL CHEMISTRY
2013Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death CANCER LETTERS
2012Salmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation. IMMUNE NETWORK
2009AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA NATURE
2008Mutations in NALP12 cause hereditary periodic fever syndromes PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
2007Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 MutantsMOLECULAR CELL
2007The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation CELL DEATH AND DIFFERENTIATION
2006Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerizationCELL DEATH AND DIFFERENTIATION
2004Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism JOURNAL OF BIOLOGICAL CHEMISTRY
2001Iron Chlorin e6 Scavenges Hydroxyl Radical and Protects Human Endothelial Cells against Hydrogen Peroxide Toxicity BIOLOGICAL & PHARMACEUTICAL BULLETIN