| 2025 | Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice
| NATURE COMMUNICATIONS |
| 2024 | Hyperglycemia enhances brain susceptibility to lipopolysaccharide-induced neuroinflammation via astrocyte reprogramming
| JOURNAL OF NEUROINFLAMMATION |
| 2024 | Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis
| EXPERIMENTAL AND MOLECULAR MEDICINE |
| 2024 | Varicella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity
| CELL DEATH & DISEASE |
| 2023 | Extracellular Acidification Augments NLRP3-Mediated Inflammasome Signaling in Macrophages
| IMMUNE NETWORK |
| 2023 | NLRP3 Exacerbate NETosis-Associated Neuroinflammation in an LPS-Induced Inflamed Brain
| IMMUNE NETWORK |
| 2023 | Distinctive role of inflammation in tissue repair and regeneration | ARCHIVES OF PHARMACAL RESEARCH |
| 2022 | Therapeutic effect of NLRP3 inhibition on hearing loss induced by systemic inflammation in a CAPS-associated mouse model
| EBIOMEDICINE |
| 2022 | Design and synthesis of an N-benzyl 5-(4-sulfamoylbenzylidene-2-thioxothiazolidin-4-one scaffold as a novel NLRP3 inflammasome inhibitor | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS |
| 2022 | Differential Regional Vulnerability of the Brain to Mild Neuroinflammation Induced by Systemic LPS Treatment in Mice
| JOURNAL OF INFLAMMATION RESEARCH |
| 2022 | Short Term Isocaloric Ketogenic Diet Modulates NLRP3 Inflammasome Via B-hydroxybutyrate and Fibroblast Growth Factor 21
| FRONTIERS IN IMMUNOLOGY |
| 2022 | PGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis
| CELL DEATH & DISEASE |
| 2021 | Intracellular NAD + Depletion Confers a Priming Signal for NLRP3 Inflammasome Activation
| FRONTIERS IN IMMUNOLOGY |
| 2021 | Antimicrobial Peptide LL-37 Drives Rosacea-Like Skin Inflammation in an NLRP3-Dependent Manner | JOURNAL OF INVESTIGATIVE DERMATOLOGY |
| 2021 | Neutrophils Facilitate Prolonged Inflammasome Response in the DAMP-Rich Inflammatory Milieu
| FRONTIERS IN IMMUNOLOGY |
| 2021 | Distinct Features of Brain-Resident Macrophages: Microglia and Non-Parenchymal Brain Macrophages
| MOLECULES AND CELLS |
| 2021 | SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models
| EMBO MOLECULAR MEDICINE |
| 2020 | Antiviral efficacy of orally delivered neoagarohexaose, a nonconventional TLR4 agonist, against norovirus infection in mice | BIOMATERIALS |
| 2020 | Bacterial Outer Membrane Vesicle-Mediated Cytosolic Delivery of Flagellin Triggers Host NLRC4 Canonical Inflammasome Signaling
| FRONTIERS IN IMMUNOLOGY |
| 2020 | ATP-P2X7-Induced Inflammasome Activation Contributes to Melanocyte Death and CD8 + T-Cell Trafficking to the Skin in Vitiligo | JOURNAL OF INVESTIGATIVE DERMATOLOGY |
| 2020 | SGLT2 Inhibition Modulates NLRP3 Inflammasome Activity via Ketones and Insulin in Diabetes With Cardiovascular Disease
| NATURE COMMUNICATIONS |
| 2020 | Non-invasive in vivo imaging of caspase-1 activation enables rapid and spatiotemporal detection of acute and chronic inflammatory disorders
| BIOMATERIALS |
| 2019 | Zika Virus Impairs Host NLRP3-mediated Inflammasome Activation in an NS3-dependent Manner
| IMMUNE NETWORK |
| 2019 | Proteomics-based functional studies reveal that galectin-3 plays a protective role in the pathogenesis of intestinal Behçet's disease
| Scientific Reports |
| 2019 | Chemotherapeutic Agent Paclitaxel Mediates Priming of NLRP3 Inflammasome Activation
| FRONTIERS IN IMMUNOLOGY |
| 2019 | Brefeldin A-sensitive ER-Golgi vesicle trafficking contributes to NLRP3-dependent caspase-1 activation | FASEB JOURNAL |
| 2019 | MPTP-driven NLRP3 inflammasome activation in microglia plays a central role in dopaminergic neurodegeneration
| CELL DEATH AND DIFFERENTIATION |
| 2018 | Palmitate and minimally-modified low-density lipoprotein cooperatively promote inflammatory responses in macrophages
| PLOS ONE |
| 2018 | Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1beta in Macrophages
| JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY |
| 2017 | Advanced glycation end products impair NLRP3 inflammasome-mediated innate immune responses in macrophages | JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2017 | NLRP3 Inflammasome Contributes to Lipopolysaccharide-induced Depressive-Like Behaviors via Indoleamine 2,3-dioxygenase Induction
| INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY |
| 2017 | Immunomodulatory/anti-inflammatory effect of ZOE-based dental materials | DENTAL MATERIALS |
| 2017 | Bacterial Secretant from Pseudomonas aeruginosa Dampens Inflammasome Activation in a Quorum Sensing-Dependent Manner
| FRONTIERS IN IMMUNOLOGY |
| 2016 | Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance | ARCHIVES OF PHARMACAL RESEARCH |
| 2016 | 25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome
| NATURE COMMUNICATIONS |
| 2016 | Inflammasome activation by cell volume regulation and inflammation-associated hyponatremia: A vicious cycle | MEDICAL HYPOTHESES |
| 2016 | Dysbiosis-induced IL-33 contributes to impaired antiviral immunity in the genital mucosa
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
| 2015 | Histone deacetylase 6 negatively regulates NLRP3 inflammasome activation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
| 2015 | Rotenone-induced Impairment of Mitochondrial Electron Transport Chain Confers a Selective Priming Signal for NLRP3 Inflammasome Activation
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2015 | Defective mitochondrial fission augments NLRP3 inflammasome activation
| SCIENTIFIC REPORTS |
| 2015 | Non-transcriptional regulation of NLRP3 inflammasome signaling by IL-4 | IMMUNOLOGY AND CELL BIOLOGY |
| 2013 | Cobalt Chloride-induced Hypoxia Ameliorates NLRP3-Mediated Caspase-1 Activation in Mixed Glial Cultures
| IMMUNE NETWORK |
| 2013 | The Mitochondrial Antiviral Protein MAVS Associates with NLRP3 and Regulates Its Inflammasome Activity | JOURNAL OF IMMUNOLOGY |
| 2013 | Ribotoxic Stress through p38 Mitogen-activated Protein Kinase Activates in Vitro the Human Pyrin Inflammasome
| JOURNAL OF BIOLOGICAL CHEMISTRY |
| 2013 | Restoration of ASC expression sensitizes colorectal cancer cells to genotoxic stress-induced caspase-independent cell death
| CANCER LETTERS |
| 2012 | Salmonella Promotes ASC Oligomerization-dependent Caspase-1 Activation
| IMMUNE NETWORK |
| 2009 | AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
| NATURE |
| 2008 | Mutations in NALP12 cause hereditary periodic fever syndromes
| PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
| 2007 | Pyrin Activates the ASC Pyroptosome in Response to Engagement by Autoinflammatory PSTPIP1 Mutants | MOLECULAR CELL |
| 2007 | The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
| CELL DEATH AND DIFFERENTIATION |
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