2023 | Fecal microbiota transplantation improves hepatic fibro-inflammation via regulating oxidative stress in experimental NASH
| DIGESTIVE AND LIVER DISEASE |
2022 | Co-administration of ursodeoxycholic acid with rosuvastatin/ezetimibe in a non-alcoholic fatty liver disease model
| GASTROENTEROLOGY REPORT |
2022 | A GLP-1/GLP-2 receptor dual agonist to treat NASH: Targeting the gut-liver axis and microbiome | HEPATOLOGY |
2022 | PERK prevents hepatic lipotoxicity by activating the p62-ULK1 axis-mediated noncanonical KEAP1-Nrf2 pathway
| REDOX BIOLOGY |
2020 | SQSTM1/p62 activates NFE2L2/NRF2 via ULK1-mediated autophagic KEAP1 degradation and protects mouse liver from lipotoxicity | AUTOPHAGY |
2020 | Ezetimibe ameliorates lipid accumulation during adipogenesis by regulating the AMPK-mTORC1 pathway | FASEB JOURNAL |
2020 | Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity | AUTOPHAGY |
2019 | InactivationofSirtuin2protectsmicefromacetaminophen-inducedliverinjury:possibleinvolvementofERstressandS6K2activation
| BMB REPORTS |
2019 | Implantable Vascularized Liver Chip for Cross‐Validation of Disease Treatment with Animal Model | ADVANCED FUNCTIONAL MATERIALS |
2019 | Repositioningofniclosamideethanolamine(NEN), ananthelminticdrug, for thetreatmentoflipotoxicity | FREE RADICAL BIOLOGY AND MEDICINE |
2018 | CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes.
| PLOS ONE |
2018 | The Antidiabetic Drug Lobeglitazone Protects Mice From Lipogenesis-Induced Liver Injury via Mechanistic Target of Rapamycin Complex 1 Inhibition.
| FRONTIERS IN ENDOCRINOLOGY |
2017 | The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity
| BMB REPORTS |
2016 | p62/SQSTM1 is required for the protection against endoplasmic reticulum stress-induced apoptotic cell death | FREE RADICAL RESEARCH |
2016 | Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis | FREE RADICAL BIOLOGY AND MEDICINE |
2015 | Concerted action of p62 and Nrf2 protects cells from palmitic acid-induced lipotoxicity | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
2015 | PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1 | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |
2015 | Fenofibrate activates Nrf2 through p62-dependent Keap1 degradation | BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS |