Cited 7 times in
Differential association between metabolic syndrome and coronary artery disease evaluated with cardiac computed tomography according to the presence of diabetes in a symptomatic Korean population
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김영진 | - |
dc.contributor.author | 성지민 | - |
dc.contributor.author | 신상훈 | - |
dc.contributor.author | 심지영 | - |
dc.contributor.author | 원기범 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 정남식 | - |
dc.contributor.author | 조인정 | - |
dc.contributor.author | 최병욱 | - |
dc.contributor.author | 홍그루 | - |
dc.date.accessioned | 2015-01-06T17:15:33Z | - |
dc.date.available | 2015-01-06T17:15:33Z | - |
dc.date.issued | 2014 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/99638 | - |
dc.description.abstract | BACKGROUND: Metabolic syndrome (MetS) is associated with increased risks of diabetes and coronary artery disease (CAD). Despite the controversial inclusion of established diabetes in MetS, the association between MetS and CAD according to diabetes status has not been elucidated in the Asian population. METHODS: We evaluated the association between MetS and CAD using the parameters including any plaque, obstructive plaque, and coronary artery calcium score (CACS) >100 according to diabetes status in 2,869 symptomatic Korean subjects who underwent cardiac computed tomographic angiography. RESULTS: The prevalence of MetS was significantly higher in the diabetic subjects than in the non-diabetic subjects (69% vs. 34%, P <0.001). The incidence of any plaque (64% vs. 43%, P <0.001), obstructive plaque (26% vs. 13%, P = 0.006), and CACS >100 (23% vs. 12%, P = 0.012) was significantly higher in diabetic subjects than in non-diabetic subjects. Among the MetS components, decreased high-density lipoprotein level was significantly associated with any plaque (odds ratio [OR] 1.35), obstructive plaque (OR 1.55), and CACS >100 (OR 1.57) in the non-diabetic subjects (P <0.01, respectively). However, none of the MetS components were associated with all the parameters in the diabetic subjects. Multivariate regression analysis revealed that MetS and the number of MetS components (MetSN) were independently associated with any plaque (MetS: OR 1.55, P <0.001; MetSN: OR 1.22, P <0.001), obstructive plaque (MetS: OR 1.52, P = 0.003; MetSN: OR 1.25, P <0.001), and CACS >100 (MetS: OR 1.46, P = 0.015; MetSN: OR 1.21, P = 0.004) only in the non-diabetic subjects, respectively. CONCLUSIONS: MetS was independently associated with the presence and severity of CAD only in the non-diabetic subjects among the symptomatic Korean population. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1~10 | - |
dc.relation.isPartOf | BMC CARDIOVASCULAR DISORDERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Chi-Square Distribution | - |
dc.subject.MESH | Coronary Angiography/methods* | - |
dc.subject.MESH | Coronary Artery Disease/diagnostic imaging* | - |
dc.subject.MESH | Coronary Artery Disease/epidemiology* | - |
dc.subject.MESH | Coronary Vessels/diagnostic imaging* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Diabetes Mellitus/diagnosis | - |
dc.subject.MESH | Diabetes Mellitus/epidemiology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Lipoproteins, HDL/blood | - |
dc.subject.MESH | Logistic Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Metabolic Syndrome/blood | - |
dc.subject.MESH | Metabolic Syndrome/diagnosis | - |
dc.subject.MESH | Metabolic Syndrome/epidemiology* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multidetector Computed Tomography* | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Odds Ratio | - |
dc.subject.MESH | Plaque, Atherosclerotic | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Vascular Calcification/diagnostic imaging | - |
dc.subject.MESH | Vascular Calcification/epidemiology | - |
dc.title | Differential association between metabolic syndrome and coronary artery disease evaluated with cardiac computed tomography according to the presence of diabetes in a symptomatic Korean population | - |
dc.type | Article | - |
dc.contributor.college | Researcher Institutes (부설 연구소) | - |
dc.contributor.department | Yonsei Cardiovascular Research Institute (심혈관연구소) | - |
dc.contributor.googleauthor | Ki-Bum Won | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Jimin Sung | - |
dc.contributor.googleauthor | Sanghoon Shin | - |
dc.contributor.googleauthor | In-Jeong Cho | - |
dc.contributor.googleauthor | Chi-Young Shim | - |
dc.contributor.googleauthor | Geu-Ru Hong | - |
dc.contributor.googleauthor | Young Jin Kim | - |
dc.contributor.googleauthor | Byung-Wook Choi | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1186/1471-2261-14-105 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02107 | - |
dc.contributor.localId | A02213 | - |
dc.contributor.localId | A02429 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A03892 | - |
dc.contributor.localId | A04059 | - |
dc.contributor.localId | A04386 | - |
dc.contributor.localId | A00727 | - |
dc.contributor.localId | A01955 | - |
dc.relation.journalcode | J00352 | - |
dc.identifier.eissn | 1471-2261 | - |
dc.identifier.pmid | 25138993 | - |
dc.subject.keyword | Metabolic syndrome | - |
dc.subject.keyword | Diabetes | - |
dc.subject.keyword | Coronary artery disease | - |
dc.subject.keyword | Coronary computed tomographic angiography | - |
dc.contributor.alternativeName | Kim, Young Jin | - |
dc.contributor.alternativeName | Sung, Ji Min | - |
dc.contributor.alternativeName | Shin, Sang Hoon | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Won, Ki Bum | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Cho, In Jeong | - |
dc.contributor.alternativeName | Choi, Byoung Wook | - |
dc.contributor.alternativeName | Hong, Geu Ru | - |
dc.contributor.affiliatedAuthor | Shin, Sang Hoon | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.contributor.affiliatedAuthor | Won, Ki Bum | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Cho, In Jeong | - |
dc.contributor.affiliatedAuthor | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | Hong, Geu Ru | - |
dc.contributor.affiliatedAuthor | Kim, Young Jin | - |
dc.contributor.affiliatedAuthor | Sung, Ji Min | - |
dc.citation.volume | 14 | - |
dc.citation.number | 105 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 10 | - |
dc.identifier.bibliographicCitation | BMC CARDIOVASCULAR DISORDERS, Vol.14(105) : 1-10, 2014 | - |
dc.identifier.rimsid | 56531 | - |
dc.type.rims | ART | - |
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