4 348

Cited 11 times in

Association between skeletal muscle mass and radial augmentation index in an elderly Korean population

Authors
 Seung Won Lee  ;  Yoosik Youm  ;  Chang Oh Kim  ;  Won Joon Lee  ;  Wungrak Choi  ;  Sang Hui Chu  ;  Yeong-Ran Park  ;  Hyeon Chang Kim 
Citation
 ARCHIVES OF GERONTOLOGY AND GERIATRICS, Vol.59(1) : 49-55, 2014 
Journal Title
 ARCHIVES OF GERONTOLOGY AND GERIATRICS 
ISSN
 0167-4943 
Issue Date
2014
MeSH
Aged ; Aged, 80 and over ; Aging/physiology* ; Biomarkers/blood ; Blood Pressure Determination ; Body Mass Index ; Cross-Sectional Studies ; Electric Impedance ; Female ; Geriatric Assessment ; Humans ; Male ; Middle Aged ; Muscle, Skeletal/anatomy & histology* ; Republic of Korea ; Risk Factors ; Sarcopenia/physiopathology* ; Sex Factors ; Surveys and Questionnaires ; Systole/physiology* ; Vascular Stiffness
Keywords
Arterial stiffness ; Augmentation index ; Elderly ; Korea ; Muscle mass ; Sarcopenia
Abstract
Increasing evidence supports the importance of maintaining skeletal muscle mass for cardiovascular health. However, there is limited data on the relationship between skeletal muscle mass and arterial stiffness targeting an elderly population. Thus, we investigated the association between skeletal muscle mass and arterial stiffness in an elderly Korean population. This study used data from the Korean Social Life, Health and Aging Project which started in 2011. In this cross-sectional study, 180 men (mean age 71.7) and 247 women (mean age 70.9) were included. Arm and leg muscle masses were measured by bioelectrical impedance analysis. Radial augmentation index, a noninvasive measure of arterial stiffness, was assessed by radial pulse wave analysis. The relationship between skeletal muscle mass and augmentation index was investigated by multiple linear regression analysis. In men, limb muscle mass was significantly and inversely associated with augmentation index (β = −1.07% per 1 kg muscle mass, p < 0.001) when adjusted for age. This inverse association remained after additional adjustment for body mass index, systolic blood pressure, total cholesterol, high-density lipoprotein-cholesterol, fasting glucose, insulin, smoking and alcohol intake (β = −0.69%, p = 0.019). In women, the inverse association between limb muscle mass and augmentation index was less prominent (β = −0.59%, p = 0.030), and the association disappeared when fully adjusted (β = −0.32%, p = 0.304). However, limb muscle mass was not associated with resting blood pressure either in men or women. Our results suggest that decreased skeletal muscle mass may affect arterial wall elasticity.
Full Text
http://www.sciencedirect.com/science/article/pii/S0167494314000090
DOI
10.1016/j.archger.2014.01.008
Appears in Collections:
3. College of Nursing (간호대학) > Dept. of Nursing (간호학과) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chang Oh(김창오) ORCID logo https://orcid.org/0000-0002-0773-5443
Kim, Hyeon Chang(김현창) ORCID logo https://orcid.org/0000-0001-7867-1240
Lee, Won Joon(이원준)
Choi, Wungrak(최웅락) ORCID logo https://orcid.org/0000-0002-3015-2502
Chu, Sang Hui(추상희) ORCID logo https://orcid.org/0000-0001-6877-5599
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/98972
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse