4 462

Cited 53 times in

Clinical and Spectral-Domain Optical Coherence Tomography Findings in Patients with Focal Choroidal Excavation

Authors
 Christopher Seungkyu Lee  ;  Se Joon Woo  ;  Yong-Kyu Kim  ;  Duck Jin Hwang  ;  Hae Min Kang  ;  Hyesun Kim  ;  Sung Chul Lee 
Citation
 OPHTHALMOLOGY, Vol.121(5) : 1029-1035, 2014 
Journal Title
OPHTHALMOLOGY
ISSN
 0161-6420 
Issue Date
2014
MeSH
Adult ; Aged ; Central Serous Chorioretinopathy/diagnosis ; Choroid/abnormalities* ; Choroid/pathology ; Choroid Diseases/diagnosis* ; Choroidal Neovascularization/diagnosis ; Coloring Agents ; Eye Abnormalities/diagnosis* ; Female ; Fluorescein Angiography ; Humans ; Indocyanine Green ; Intraocular Pressure/physiology ; Male ; Middle Aged ; Organ Size ; Polyps/diagnosis ; Retrospective Studies ; Tomography, Optical Coherence* ; Visual Acuity/physiology
Abstract
OBJECTIVE:
To describe the clinical and spectral-domain optical coherence tomography (SD-OCT) findings in patients with focal choroidal excavation (FCE).
DESIGN:
Retrospective case series.
PARTICIPANTS:
Forty-one eyes of 38 patients with FCE identified in 2 tertiary medical centers in Korea.
METHODS:
Clinical features, SD-OCT findings, and associated macular disorders of FCE were analyzed and detailed.
MAIN OUTCOME MEASURES:
Statistical associations among clinical features, including lesion type, size, and choroidal thickness, and frequency of association with central serous chorioretinopathy (CSC), choroidal neovascularization (CNV), and polypoidal choroidal vasculopathy (PCV).
RESULTS:
Mean patient age was 50.1 years (range, 25-76 years). The mean spherical equivalent of refractive error was -3.7 diopters (range, -10.0 to +1.5 diopters). Three patients (8%) had bilateral lesions, and 1 patient (3%) had 2 distinct lesions in the same eye. The mean FCE width and depth were 757 μm and 107 μm, respectively, with a positive correlation between width and depth (P = 0.003). The mean subfoveal choroidal thickness of FCE eyes was 284 μm, which was not statistically different from that of age-, sex-, and refractive error-matched normal subjects. Choroidal thickness in FCE was less in eyes with hyperreflective choroidal tissue under the excavation that was present in 22 eyes (54%) versus eyes without excavation (128 vs. 190 μm, respectively; P = 0.009). Twelve FCEs (29%) were the nonconforming type, revealing separation between the photoreceptor tips and the retinal pigment epithelium on SD-OCT. Nonconforming FCE was associated with visual symptoms (P < 0.001) and the presence of concurrent CSC (P = 0.001). Ten eyes (24%) were associated with CSC, and 9 eyes (22%) were associated with CNV, including 1 eye with PCV features. One eye with FCE and type 1 CNV developed a new excavation, and the excavated area in 1 eye with PCV enlarged slightly during follow-up.
CONCLUSIONS:
Focal choroidal excavation is a relatively common entity and frequently associated with choroidal diseases, including CSC, CNV, and PCV. Although FCE is classically thought to be a congenital malformation, acquired FCE forms possibly exist.
Full Text
http://www.sciencedirect.com/science/article/pii/S016164201301169X
DOI
10.1016/j.ophtha.2013.11.043
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Hae Min(강혜민)
Kim, Hye Sun(김혜선)
Lee, Sung Chul(이성철) ORCID logo https://orcid.org/0000-0001-9438-2385
Lee, Christopher Seungkyu(이승규) ORCID logo https://orcid.org/0000-0001-5054-9470
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/98836
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links