Cited 76 times in
Clinical and Spectral-Domain Optical Coherence Tomography Findings in Patients with Focal Choroidal Excavation
DC Field | Value | Language |
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dc.contributor.author | 강혜민 | - |
dc.contributor.author | 김혜선 | - |
dc.contributor.author | 이성철 | - |
dc.contributor.author | 이승규 | - |
dc.date.accessioned | 2015-01-06T16:49:22Z | - |
dc.date.available | 2015-01-06T16:49:22Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 0161-6420 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/98836 | - |
dc.description.abstract | OBJECTIVE: To describe the clinical and spectral-domain optical coherence tomography (SD-OCT) findings in patients with focal choroidal excavation (FCE). DESIGN: Retrospective case series. PARTICIPANTS: Forty-one eyes of 38 patients with FCE identified in 2 tertiary medical centers in Korea. METHODS: Clinical features, SD-OCT findings, and associated macular disorders of FCE were analyzed and detailed. MAIN OUTCOME MEASURES: Statistical associations among clinical features, including lesion type, size, and choroidal thickness, and frequency of association with central serous chorioretinopathy (CSC), choroidal neovascularization (CNV), and polypoidal choroidal vasculopathy (PCV). RESULTS: Mean patient age was 50.1 years (range, 25-76 years). The mean spherical equivalent of refractive error was -3.7 diopters (range, -10.0 to +1.5 diopters). Three patients (8%) had bilateral lesions, and 1 patient (3%) had 2 distinct lesions in the same eye. The mean FCE width and depth were 757 μm and 107 μm, respectively, with a positive correlation between width and depth (P = 0.003). The mean subfoveal choroidal thickness of FCE eyes was 284 μm, which was not statistically different from that of age-, sex-, and refractive error-matched normal subjects. Choroidal thickness in FCE was less in eyes with hyperreflective choroidal tissue under the excavation that was present in 22 eyes (54%) versus eyes without excavation (128 vs. 190 μm, respectively; P = 0.009). Twelve FCEs (29%) were the nonconforming type, revealing separation between the photoreceptor tips and the retinal pigment epithelium on SD-OCT. Nonconforming FCE was associated with visual symptoms (P < 0.001) and the presence of concurrent CSC (P = 0.001). Ten eyes (24%) were associated with CSC, and 9 eyes (22%) were associated with CNV, including 1 eye with PCV features. One eye with FCE and type 1 CNV developed a new excavation, and the excavated area in 1 eye with PCV enlarged slightly during follow-up. CONCLUSIONS: Focal choroidal excavation is a relatively common entity and frequently associated with choroidal diseases, including CSC, CNV, and PCV. Although FCE is classically thought to be a congenital malformation, acquired FCE forms possibly exist. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1029~1035 | - |
dc.relation.isPartOf | OPHTHALMOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Central Serous Chorioretinopathy/diagnosis | - |
dc.subject.MESH | Choroid/abnormalities* | - |
dc.subject.MESH | Choroid/pathology | - |
dc.subject.MESH | Choroid Diseases/diagnosis* | - |
dc.subject.MESH | Choroidal Neovascularization/diagnosis | - |
dc.subject.MESH | Coloring Agents | - |
dc.subject.MESH | Eye Abnormalities/diagnosis* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorescein Angiography | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Indocyanine Green | - |
dc.subject.MESH | Intraocular Pressure/physiology | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Organ Size | - |
dc.subject.MESH | Polyps/diagnosis | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Tomography, Optical Coherence* | - |
dc.subject.MESH | Visual Acuity/physiology | - |
dc.title | Clinical and Spectral-Domain Optical Coherence Tomography Findings in Patients with Focal Choroidal Excavation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학) | - |
dc.contributor.googleauthor | Christopher Seungkyu Lee | - |
dc.contributor.googleauthor | Se Joon Woo | - |
dc.contributor.googleauthor | Yong-Kyu Kim | - |
dc.contributor.googleauthor | Duck Jin Hwang | - |
dc.contributor.googleauthor | Hae Min Kang | - |
dc.contributor.googleauthor | Hyesun Kim | - |
dc.contributor.googleauthor | Sung Chul Lee | - |
dc.identifier.doi | 10.1016/j.ophtha.2013.11.043 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00095 | - |
dc.contributor.localId | A02873 | - |
dc.contributor.localId | A02913 | - |
dc.contributor.localId | A01173 | - |
dc.relation.journalcode | J02432 | - |
dc.identifier.eissn | 1549-4713 | - |
dc.identifier.pmid | 24439757 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S016164201301169X | - |
dc.contributor.alternativeName | Kang, Hae Min | - |
dc.contributor.alternativeName | Kim, Hye Sun | - |
dc.contributor.alternativeName | Lee, Sung Chul | - |
dc.contributor.alternativeName | Lee, Seung Kyu | - |
dc.contributor.affiliatedAuthor | Kang, Hae Min | - |
dc.contributor.affiliatedAuthor | Lee, Sung Chul | - |
dc.contributor.affiliatedAuthor | Lee, Seung Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Hye Sun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 121 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1029 | - |
dc.citation.endPage | 1035 | - |
dc.identifier.bibliographicCitation | OPHTHALMOLOGY, Vol.121(5) : 1029-1035, 2014 | - |
dc.identifier.rimsid | 38814 | - |
dc.type.rims | ART | - |
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