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Two-Year Outcomes of Deep Brain Stimulation in Adults With Cerebral Palsy

Authors
 Ae Ryoung Kim  ;  Jin Woo Chang  ;  Won Seok Chang  ;  Eun Sook Park  ;  Sung-Rae Cho 
Citation
 Annals of Rehabilitation Medicine, Vol.38(2) : 209-217, 2014 
Journal Title
Annals of Rehabilitation Medicine
ISSN
 2234-0645 
Issue Date
2014
Keywords
Cerebral palsy ; Deep brain stimulation ; Dystonia ; Dystonia rating scale
Abstract
OBJECTIVE:
To investigate the effect of deep brain stimulation (DBS) on reducing dystonia and disability in adults with cerebral palsy (CP) and to compare the therapeutic outcomes between primary dystonia patients and CP patients over two years after bilateral pallidal DBS.
METHODS:
Five patients with primary dystonia and seven CP patients with dystonia were recruited. All subjects received DBS surgery in both globus pallidus. Burke-Fahn-Marsden dystonia rating scale consisting of dystonia movement score and disability score and subjective satisfaction scale were assessed after 1 month and every 6 months over two years following DBS treatment.
RESULTS:
On the dystonia movement scale, both groups of primary dystonia patients and CP patients showed a significant decrease over time following DBS. On the disability scale, patients with primary dystonia showed a significant decrease over time, whereas the disability score of CP patients did not change over the two years. Comparing the dystonia movement and disability scores of CP patients at each assessment, patients with primary dystonia showed a significant reduction after 6 months. Comparing the satisfaction scores of CP patients after DBS, patients with primary dystonia showed significantly higher subjective satisfaction.
CONCLUSION:
Whereas dystonia can be significantly reduced in patients with primary dystonia, CP patients showed a modest improvement on the dystonia movement scale, but not on the disability scale. Therefore, DBS may be considered with caution as a treatment modality of CP patients with dystonia.
Files in This Item:
T201401561.pdf Download
DOI
10.5535/arm.2014.38.2.209
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ae Ryoung(김애령)
Park, Eun Sook(박은숙) ORCID logo https://orcid.org/0000-0002-9144-3063
Chang, Won Seok(장원석) ORCID logo https://orcid.org/0000-0003-3145-4016
Chang, Jin Woo(장진우) ORCID logo https://orcid.org/0000-0002-2717-0101
Cho, Sung-Rae(조성래) ORCID logo https://orcid.org/0000-0003-1429-2684
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/98827
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