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T1 and T2 Dual-mode MRI Contrast Agent for Enhancing Accuracy by Engineered Nanomaterials

DC FieldValueLanguage
dc.contributor.author김일선-
dc.contributor.author박국인-
dc.contributor.author송호택-
dc.contributor.author윤석환-
dc.date.accessioned2015-01-06T16:48:44Z-
dc.date.available2015-01-06T16:48:44Z-
dc.date.issued2014-
dc.identifier.issn1936-0851-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/98816-
dc.description.abstractOne of the holy grails in biomedical imaging technology is to achieve accurate imaging of biological targets. The development of sophisticated instrumentation and the use of contrast agents have improved the accuracy of biomedical imaging. However, the issue of false imaging remains a problem. Here, we developed a dual-mode artifact filtering nanoparticle imaging agent (AFIA) that comprises a combination of paramagnetic and superparamagnetic nanomaterials. This AFIA has the ability to perform “AND logic gate” algorithm to eliminate false errors (artifacts) from the raw images to enhance accuracy of the MRI. We confirm the artifact filtering capability of AFIA in MRI phantoms and further demonstrate that artifact-free imaging of stem cell migration is possible in vivo.-
dc.description.statementOfResponsibilityopen-
dc.format.extent3393~3401-
dc.relation.isPartOfACS NANO-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHArtifacts*-
dc.subject.MESHBrain/cytology-
dc.subject.MESHCell Tracking-
dc.subject.MESHContrast Media*/chemistry-
dc.subject.MESHEmbryonic Stem Cells/cytology-
dc.subject.MESHEngineering*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMagnetic Resonance Imaging/methods*-
dc.subject.MESHMagnets/chemistry-
dc.subject.MESHManganese/chemistry-
dc.subject.MESHModels, Molecular-
dc.subject.MESHMolecular Conformation-
dc.subject.MESHNanoparticles*/chemistry-
dc.subject.MESHOrganometallic Compounds/chemistry-
dc.subject.MESHPregnancy-
dc.subject.MESHRats-
dc.titleT1 and T2 Dual-mode MRI Contrast Agent for Enhancing Accuracy by Engineered Nanomaterials-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorTae-Hyun Shin-
dc.contributor.googleauthorJin-sil Choi-
dc.contributor.googleauthorSeokhwan Yun-
dc.contributor.googleauthorIl-Sun Kim-
dc.contributor.googleauthorHo-Taek Song-
dc.contributor.googleauthorYoungmee Kim-
dc.contributor.googleauthorKook In Park-
dc.contributor.googleauthorJinwoo Cheon-
dc.identifier.doi10.1021/nn405977t-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00849-
dc.contributor.localIdA01438-
dc.contributor.localIdA02080-
dc.contributor.localIdA02565-
dc.relation.journalcodeJ00005-
dc.identifier.eissn1936-086X-
dc.identifier.pmid24673493-
dc.identifier.urlhttp://pubs.acs.org/doi/abs/10.1021/nn405977t-
dc.contributor.alternativeNameKim, Il Sun-
dc.contributor.alternativeNamePark, Kook In-
dc.contributor.alternativeNameSong, Ho Taek-
dc.contributor.alternativeNameYun, Seok Hwan-
dc.contributor.affiliatedAuthorKim, Il Sun-
dc.contributor.affiliatedAuthorPark, Kook In-
dc.contributor.affiliatedAuthorSong, Ho Taek-
dc.contributor.affiliatedAuthorYun, Seok Hwan-
dc.rights.accessRightsfree-
dc.citation.volume8-
dc.citation.number4-
dc.citation.startPage3393-
dc.citation.endPage3401-
dc.identifier.bibliographicCitationACS NANO, Vol.8(4) : 3393-3401, 2014-
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers

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