1 499

Cited 5 times in

Heterogeneous echogenicity of the thyroid parenchyma does not influence the detection of multi-focality in papillary thyroid carcinoma on preoperative ultrasound staging

Authors
 Sun Jin Herh  ;  Eun-Kyung Kim  ;  Ji Min Sung  ;  Jung Hyun Yoon  ;  Hee Jung Moon  ;  Jin Young Kwak 
Citation
 ULTRASOUND IN MEDICINE AND BIOLOGY, Vol.40(5) : 884-889, 2014 
Journal Title
ULTRASOUND IN MEDICINE AND BIOLOGY
ISSN
 0301-5629 
Issue Date
2014
MeSH
Adolescent ; Adult ; Aged ; Aged, 80 and over ; Carcinoma/diagnostic imaging* ; Carcinoma/pathology* ; Carcinoma, Papillary ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Neoplasm Staging ; Observer Variation ; Predictive Value of Tests ; Preoperative Care/methods* ; Retrospective Studies ; Sensitivity and Specificity ; Thyroid Gland/diagnostic imaging* ; Thyroid Gland/pathology* ; Thyroid Neoplasms/diagnostic imaging* ; Thyroid Neoplasms/pathology* ; Ultrasonography ; Young Adult
Keywords
Malignancy ; Pre-operative surveillance ; Staging ; Thyroid ; Ultrasonography
Abstract
Heterogeneous echogenicity and micro-nodulations of diffuse thyroid disease on ultrasonography (US) might influence the diagnostic performance of pre-operative US staging, especially the detection of multi-focality. This study was designed to determine whether heterogeneous echogenicity of the thyroid parenchyma influences the diagnostic performance of US in the detection of multi-focality in papillary thyroid carcinoma. Between December 2010 and April 2011, 811 patients underwent pre-operative staging US for papillary thyroid carcinoma and surgery. Twelve radiologists performed the pre-operative US for T and N staging. Underlying parenchymal echogenicity and unilateral and bilateral multi-focality of the thyroid nodules were also evaluated. Patients were divided into two groups on the basis of the underlying echogenicity of the thyroid gland. To evaluate the diagnostic accuracy of US with respect to underlying echogenicity, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy were calculated and compared between the two groups. Among the 811 patients included, US revealed underlying heterogeneous echogenicity of the thyroid parenchyma in 204 (25.2%) and underlying homogeneous echogenicity of the thyroid parenchyma in 607 (74.8%). There were no significant differences between the two groups in the diagnostic performance of pre-operative staging US in predicting unilateral multi-focality and bilaterality. Underlying heterogeneous echogenicity in a thyroid gland with Hashimoto's thyroiditis does not significantly influence the detection of multi-focality in papillary thyroid cancer on pre-operative US staging.
Full Text
http://www.sciencedirect.com/science/article/pii/S0301562913011952
DOI
10.1016/j.ultrasmedbio.2013.11.021
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kwak, Jin Young(곽진영) ORCID logo https://orcid.org/0000-0002-6212-1495
Kim, Eun-Kyung(김은경) ORCID logo https://orcid.org/0000-0002-3368-5013
Moon, Hee Jung(문희정) ORCID logo https://orcid.org/0000-0002-5643-5885
Yoon, Jung Hyun(윤정현) ORCID logo https://orcid.org/0000-0002-2100-3513
Herh, Sun Jin(허선진)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/98529
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links