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뇌 혈관조영술에서의 Iopamidol (Pamiray(R) 300)의 임상적용

Other Titles
 Cinical Application of Iopamidol (Pamiray(R) 300) for Cerebral Angiography 
 Journal of the Korean Society for Therapeutic Radiology and Oncology, Vol.57(2) : 121-127, 2007 
Journal Title
Journal of the Korean Society for Therapeutic Radiology and Oncology(대한방사선종양학회지)
Issue Date
Purpose: The aim of this study was to assess the clinical safety and efficacy of Pamiray® 300 (Iopamidol; Dongkook Pharm., Seoul, Korea) as a nonionic contrast medium for cerebral angiography.

Materials and Methods: One hundred patients undergoing cerebral angiography were randomly assigned to receive Pamiray® 300 after written consent had been obtained. Patients with adverse reactions were divided into two groups. One group consisted of patients with minor adverse events such as heat sensation and pain, and the other group consisted of patients with major adverse events such as dyspnea, laryngeal edema and shock. The qualities of the radiographic images were stratified into five grades by three independent radiologists.

Results: No abnormality induced by Pamiray® 300 was seen by a physical and neurological examination, blood pressure measurement, electrocardiogram, respiration rate measurement and partial fraction of arterial oxygen recording. No major and severe adverse events occurred throughout the study. Patient sex, age, disease category, underlying disease and administered contrast dosage showed no statistical significance with regards to the occurrence of adverse events. The opacification of blood vessels in all patients was 'good' or 'excellent'.

Conclusion: Based on the results of this study, Pamiray® 300 is a safe, efficacious and well-tolerated contrast medium for use in cerebral angiography. Thus, Pamiray® 300 can be used as a competitive medium in cerebral angiography.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Ik(김동익)
Kim, Dong Joon(김동준) ORCID logo https://orcid.org/0000-0002-7035-087X
Kim, Eung Yeop(김응엽)
Kim, Jinna(김진아) ORCID logo https://orcid.org/0000-0002-9978-4356
Suh, Sang Hyun(서상현) ORCID logo https://orcid.org/0000-0002-7098-4901
Lee, Seung Koo(이승구) ORCID logo https://orcid.org/0000-0001-5646-4072
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