146 233

Cited 0 times in

Docetaxel 투여 후 발생한 조갑하 농양 및 조갑 박리증 1예

Other Titles
 A Case of Subungal Abscess and Onycholysis Induced by Docetaxel 
Authors
 정한영  ;  이창률  ;  장윤수  ;  안철민  ;  김형중 
Citation
 Tuberculosis and Respiratory Diseases, Vol.62(2) : 125-128, 2007 
Journal Title
 Tuberculosis and Respiratory Diseases 
ISSN
 1738-3536 
Issue Date
2007
Abstract
Docetaxel is a taxoid antineoplastic drug, which is widely used to treat locally advanced or metastatic non-small cell lung cancer (NSCLC). Among the adverse dermatological reactions, nail disorders such as bending, onycholysis, hypo- or hyperpigmentation are rare. We report a case of a 62-year-old male with advanced NSCLC (cT4N3M1, stage IV), who developed purulent discharge and onycholysis in the nail of all his fingers and the left great toe after five courses of anti-neoplastic chemotherapy, which included docetaxel (cumulative dose: 370 mg/m2, 590 mg). Seven days after the final session of chemotherapy, the patient had become aware of discoloration and swelling of the nail beds with out pain. Three days later, greenish-yellow purulent discharge oozed out from the involved nails. Microbiologic studies revealed Pseudomonas aeruginosa. Intravenous and topical antibiotics (mupirocin) were applied. After 2 weeks, regrown nails were observed and the onycholysis had improved.
Files in This Item:
T200700922.pdf Download
DOI
10.4046/trd.2007.62.2.125
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
김형중(Kim, Hyung Jung) ORCID logo https://orcid.org/0000-0003-2498-0683
안철민(Ahn, Chul Min)
이창률(Lee, Chang Youl)
장윤수(Chang, Yoon Soo) ORCID logo https://orcid.org/0000-0003-3340-4223
Export
RIS (EndNote)
XLS (Excel)
XML
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97427
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse