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Diffusion-Tensor MR Imaging and Tractography: Exploring Brain Microstructure and Connectivity

Authors
 Paolo G. P. Nucifora  ;  Ragini Verma  ;  Elias R. Melhem  ;  Seung-Koo Lee 
Citation
 RADIOLOGY, Vol.245(2) : 367-384, 2007 
Journal Title
 RADIOLOGY 
ISSN
 0033-8419 
Issue Date
2007
Abstract
Diffusion magnetic resonance (MR) imaging is evolving into a potent tool in the examination of the central nervous system. Although it is often used for the detection of acute ischemia, evaluation of directionality in a diffusion measurement can be useful in white matter, which demonstrates strong diffusion anisotropy. Techniques such as diffusion-tensor imaging offer a glimpse into brain microstructure at a scale that is not easily accessible with other modalities, in some cases improving the detection and characterization of white matter abnormalities. Diffusion MR tractography offers an overall view of brain anatomy, including the degree of connectivity between different regions of the brain. However, optimal utilization of the wide range of data provided with directional diffusion MR measurements requires careful attention to acquisition and postprocessing. This article will review the principles of diffusion contrast and anisotropy, as well as clinical applications in psychiatric, developmental, neurodegenerative, neoplastic, demyelinating, and other types of disease.
Full Text
http://pubs.rsna.org/doi/abs/10.1148/radiol.2452060445
DOI
10.1148/radiol.2452060445
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Seung Koo(이승구) ORCID logo https://orcid.org/0000-0001-5646-4072
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97340
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