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Doppler ultrasonographic indices in diagnosing nutcracker syndrome in children

Authors
 Jae Il Shin  ;  Jee Min Park  ;  Myung Joon Kim  ;  Jae Seung Lee 
Citation
 PEDIATRIC NEPHROLOGY, Vol.22(3) : 409-413, 2007 
Journal Title
PEDIATRIC NEPHROLOGY
ISSN
 0931-041X 
Issue Date
2007
Abstract
To elucidate the Doppler ultrasonographic cut-off value of nutcracker syndrome causing hematuria in children, we analyzed Doppler spectral findings between 15 children with nutcracker syndrome and 15 age- and sex-matched normal control subjects. A follow-up Doppler ultrasound (US) was also performed in children with nutcracker syndrome when hematuria subsided completely after a median period of 1.7 years (range: 1.0–3.5 years) (relieved nutcracker syndrome). The peak velocity (PV) ratios of the left renal vein (LRV) were significantly higher in children with nutcracker syndrome than in those with relieved nutcracker syndrome (P < 0.0001) and normal children (P < 0.0001). The PV ratios of the LRV at the follow-up US were significantly higher than those in the control subjects (P = 0.019). None of the 15 normal children showed PV ratios of the LRV > 3.7, but five of the 15 children with relieved nutcracker syndrome without hematuria had PV ratios of 3.91–5.02. When we set the cut-off values for nutcracker syndrome at the mean ± 2 SD (mean: 2.95 ± 0.92, range: 1.60–5.02) of 30 controls (normal children and relieved nutcracker without hematuria), the calculated cut-off value was 4.8, and the sensitivity and specificity were 100% and 93%, respectively. Given its high sensitivity, renal Doppler US can be used as a useful initial non-invasive test in the diagnosis of nutcracker syndrome in children with hematuria.
Full Text
http://link.springer.com/article/10.1007%2Fs00467-006-0319-8
DOI
10.1007/s00467-006-0319-8
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myung Joon(김명준) ORCID logo https://orcid.org/0000-0002-4608-0275
Lee, Jae Seung(이재승)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97284
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