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Shape deformation of the insula in alcoholics: reduction of left-right asymmetry

Authors
 Young Chul Jung  ;  Dong-Pyo Jang  ;  Eun Lee  ;  Young-Bo Kim  ;  Zang-Hee Cho  ;  Sangjin Park  ;  Jae-Jin Kim  ;  Jeonghun Ku  ;  Kee Namkoong 
Citation
 NEUROREPORT, Vol.18(17) : 1787-1791, 2007 
Journal Title
NEUROREPORT
ISSN
 0959-4965 
Issue Date
2007
Abstract
We have investigated shape deformation of the insula to get a viewpoint of how chronic alcohol consumption affects the perisylvian region and compared the deformity pattern between the left and right hemisphere. A landmark-based structural and surface shape analysis of the insula was performed in 20 patients with alcohol dependence and 20 controls matched for age. The shape analysis revealed that the left and right insula follow distinct shape deformation patterns, which resulted in the reduction of left–right asymmetry. The shape deformity was most prominent in the central part of both insula. Our findings indicate that the right and left hemisphere are both affected but shows distinct patterns of deformation in alcohol dependence.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00001756-200711190-00007&LSLINK=80&D=ovft
DOI
10.1097/WNR.0b013e3282f193b4
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Jin(김재진) ORCID logo https://orcid.org/0000-0002-1395-4562
Namkoong, Kee(남궁기) ORCID logo https://orcid.org/0000-0003-1400-8057
Lee, Eun(이은) ORCID logo https://orcid.org/0000-0002-7462-0144
Jung, Young Chul(정영철) ORCID logo https://orcid.org/0000-0002-0578-2510
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/97200
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