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The effects of collagen membrane coated with PLGA on bone regeneration in rat calvarial defects

Authors
 Kun Young Song  ;  Yoo Jung Um  ;  Chong Kwan Kim  ;  Seong Ho Choi  ;  Yong Keun Lee  ;  Ui Won Jung 
Citation
 Key Engineering Materials, Vol.342~343 : 357-360, 2007 
Journal Title
 Key Engineering Materials 
ISSN
 1013-9826 
Issue Date
2007
Abstract
The purpose of this study was to evaluate the effects of collagen membrane coated with PLGA on bone regeneration in rat calvarial defect. Five groups of 10 animals each received either collagen membrane coated with 0.5%, 1%, 3% concentration of PLGA, collagen membrane only or surgical control. Each group of animals was healed into 2 healing periods of 2(5 animals) and 8(5 animals)weeks and histologic and histomorphometric analysis were done. The results of the following study revealed that surgical implantation of collagen membranes coated with PLGA enhanced local bone formation at both 2 and 8 weeks independent of different PLGA concentrations. In conclusion, collagen membrane coated with PLGA shows a significant bone formation behavior irrespective of their concentration.
Full Text
http://www.scientific.net/KEM.342-343.357
DOI
10.4028/www.scientific.net/KEM.342-343.357
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
Yonsei Authors
Kim, Chong Kwan(김종관)
Lee, Yong Keun(이용근)
Choi, Seong Ho(최성호) ORCID logo https://orcid.org/0000-0001-6704-6124
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96771
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