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염산레보세티리진 경구투여가 알레르기비염 환자의 삶의 질에 미치는 영향

Other Titles
 Effects of Levocetirizine on Quality of Life in the Patients with Allergic Rhinitis 
Authors
 조형주  ;  윤주헌  ;  변형권  ;  박준성  ;  박영신  ;  김의철  ;  김창훈  ;  홍천수  ;  김경수  ;  이정권  ;  박중원 
Citation
 Journal of Rhinology, Vol.14(2) : 114-121, 2007 
Journal Title
 Journal of Rhinology 
ISSN
 1225-6870 
Issue Date
2007
Abstract
Background and Objectives : Allergy is a chronic disorder with undesirable consequences on the quality of life (QoL). The first aim of this study is to evaluate the impact of allergy on the QoL and to show the correlation between symptoms and categories of the QoL. The second purpose is to determine whether treatment with levocetirizine improves the QoL among allergic rhinitis patients. Materials and Methods : A total of 412 allergic patients answered the questionnaire and its sensitivity was checked to validate its usefulness in asthma and allergic rhinitis patients. To evaluate the effect of applying levocetirizine for 1 month on the QoL among allergic rhinitis patients, a total of 94 subjects were assessed with the questionnaire and analyzed (paired t-test). To evaluate its effect on the symptoms of allergic rhinitis for the duration of 2 and 4 weeks, a total of 100 subjects were analyzed (repeated ANOVA) with the symptom questionnaire. Results: Besides the physical symptoms, patients suffered from activity restriction, emotional problems, difficulty in being examined, and dissatisfaction with health status. The correlation between the questionnaire and the QoL was statistically significant. After treatment, the QoL and symptoms, except nasal congestion, were significantly improved. Conclusion: The questionnaire can be beneficial in assessing the QoL among allergic patients. Treatment with levocetirizine provides improvement in the QoL and lowers the symptoms score among allergic rhinitis patients.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Kyung Su(김경수) ORCID logo https://orcid.org/0000-0003-1460-0640
Kim, Chang Hoon(김창훈) ORCID logo https://orcid.org/0000-0003-1238-6396
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Yoon, Joo Heon(윤주헌)
Lee, Jeung Gweon(이정권)
Cho, Hyung Ju(조형주) ORCID logo https://orcid.org/0000-0002-2851-3225
Hong, Chein Soo(홍천수)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96525
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