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Inflammatory myofibroblastic tumors in the liver: MRI of two immunohistochemically-verified cases

Authors
 Jeong-Sik Yu  ;  Chanil Park  ;  Ki Whang Kim  ;  Jae-Joon Chung  ;  Joo Hee Kim 
Citation
 JOURNAL OF MAGNETIC RESONANCE IMAGING, Vol.26(2) : 418-421, 2007 
Journal Title
 JOURNAL OF MAGNETIC RESONANCE IMAGING 
ISSN
 1053-1807 
Issue Date
2007
MeSH
Adult ; Cell Proliferation ; Contrast Media/pharmacology ; Fibroblasts/pathology* ; Humans ; Image Processing, Computer-Assisted ; Immunohistochemistry/methods* ; Inflammation ; Liver/pathology ; Liver Neoplasms/diagnosis* ; Liver Neoplasms/pathology* ; Magnetic Resonance Imaging/methods* ; Male ; Middle Aged ; Necrosis ; Phenotype
Abstract
In immunohistochemically-proven hepatic inflammatory myofibroblastic tumors, MRI revealed layered patterns of contrast enhancement during dynamic imaging, consisting of outer hypovascular rind and inner hypervascular stroma and mimicking the imaging features of pyogenic organized abscess with deficient central necrosis in four lesions in two patients. For the outer hypovascular rind, T2-weighted images showed hyperintensity, suggesting immature fibrosis corresponding to the area of arterial hypovascularity and delayed contrast enhancement. The patients' favorable clinical course and imaging findings reflected the benign nature of these lesions, from an infectious origin, despite the phenotypic expression of myofibroblastic proliferation in the hypervascular stroma containing chronic inflammatory cells.
Full Text
http://onlinelibrary.wiley.com/doi/10.1002/jmri.21023/abstract
DOI
10.1002/jmri.21023
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Ki Whang(김기황)
Kim, Joo Hee(김주희) ORCID logo https://orcid.org/0000-0001-5383-3602
Park, Chan Il(박찬일)
Yu, Jeong Sik(유정식) ORCID logo https://orcid.org/0000-0002-8171-5838
Chung, Jae Joon(정재준) ORCID logo https://orcid.org/0000-0002-7447-1193
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96466
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