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Efficacy of multidetector row computed tomography of the spine in patients with multiple myeloma: Comparison with magnetic resonance imaging and fluorodeoxyglucose-positron emission tomography

Authors
 Jin Hur  ;  Choon-Sik Yoon  ;  Jin-Suck Suh  ;  Mi Jin Yun  ;  Young Hoon Ryu 
Citation
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.31(3) : 342-347, 2007 
Journal Title
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY 
ISSN
 0363-8715 
Issue Date
2007
MeSH
Aged ; Contrast Media ; Female ; Fluorodeoxyglucose F18 ; Gadolinium DTPA ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Multiple Myeloma/diagnosis ; Multiple Myeloma/diagnostic imaging* ; Positron-Emission Tomography ; Radiopharmaceuticals ; Sensitivity and Specificity ; Spinal Neoplasms/diagnosis ; Spinal Neoplasms/diagnostic imaging* ; Tomography, X-Ray Computed/methods*
Abstract
PURPOSE: The aim of our study was to compare the efficacy of multidetector row computed tomography (MDCT) with magnetic resonance imaging (MRI) and fluorodeoxyglucose-positron emission tomography (FDG-PET) for detection of spinal bone marrow involvement in patients with multiple myeloma. MATERIALS AND METHODS: Ten patients with multiple myeloma stage III underwent MDCT and MRI of the spine and FDG-PET. The number and location of lesions detected by 3 modalities were recorded, and a lesion-by-lesion analysis was completed, using McNemar test. For MDCT, image analysis was performed according to the type of lesion (established by Laroche et al), and the efficacy of lesion detection was compared with that of the MRI and FDG-PET. P values less than 0.05 were considered statistically significant. RESULTS: The MDCT, MRI, and FDG-PET detected the following numbers of lesions: 102 of 140 vertebrae, 95 of 140 vertebrae, and 84 of 140 vertebrae, respectively. The difference between the abilities of MDCT and MRI to detect lesions was not statistically significant (P = 0.289). However, the difference in effectiveness between MDCT and FDG-PET was statistically significant (P < 0.001). For small osteolytic lesions, less than 5 mm, the difference in effectiveness between MDCT and MRI was also statistically significant (P = 0.031). CONCLUSIONS: The MDCT is very sensitive in detecting small osteolytic lesions in the spine, as compared with MRI and FDG-PET.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-200705000-00003&LSLINK=80&D=ovft
DOI
10.1097/01.rct.0000237820.41549.c9
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Suh, Jin Suck(서진석) ORCID logo https://orcid.org/0000-0001-9455-9240
Ryu, Young Hoon(유영훈) ORCID logo https://orcid.org/0000-0002-9000-5563
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
Yoon, Choon Sik(윤춘식) ORCID logo https://orcid.org/0000-0003-2010-6710
Hur, Jin(허진) ORCID logo https://orcid.org/0000-0002-8651-6571
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/96282
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