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Synthesis of ultrasensitive magnetic resonance contrast agents for cancer imaging using PEG-fatty acid

DC Field Value Language
dc.contributor.author서진석-
dc.contributor.author양재문-
dc.contributor.author윤호근-
dc.contributor.author허용민-
dc.date.accessioned2014-12-21T16:30:52Z-
dc.date.available2014-12-21T16:30:52Z-
dc.date.issued2007-
dc.identifier.issn0897-4756-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/95832-
dc.description.abstractDiagnosis of cancer in the early stages requires sensitive magnetic resonance (MR) probes to detect low concentrations of magnetic substances. In this study, ultrasensitive magnetic resonance contrast agents (UMRCAs) composed of magnetic nanocrystals and amphiphilic block copolymers were synthesized for cancer detection using polyethylene glycol and fatty acid. The chemical structures and the compositions of PEGylated magnetic nanoparticles were analyzed. UMRCAs displayed remarkable colloidal stability and high sensitivity as MR probes. Furthermore, UMRCAs exhibited low cytotoxicity and excellent cancer detection ability in an in vivo animal model-
dc.description.statementOfResponsibilityopen-
dc.format.extent3870~3876-
dc.relation.isPartOfCHEMISTRY OF MATERIALS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSynthesis of ultrasensitive magnetic resonance contrast agents for cancer imaging using PEG-fatty acid-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Biochemistry & Molecular Biology (생화학,분자생물학)-
dc.contributor.googleauthorJaemoon Yang-
dc.contributor.googleauthorTong-Il Lee-
dc.contributor.googleauthorSeungjoo Haam-
dc.contributor.googleauthorMin Yong Huh-
dc.contributor.googleauthorHo-Geun Yoon-
dc.contributor.googleauthorJin-Suck Suh-
dc.contributor.googleauthorYong Jin Song-
dc.contributor.googleauthorChoong-Hwan Lee-
dc.contributor.googleauthorWoochan Hyung-
dc.contributor.googleauthorEun-Kyung Lim-
dc.contributor.googleauthorJaemin Lee-
dc.identifier.doi10.1021/cm070495s-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01916-
dc.contributor.localIdA02625-
dc.contributor.localIdA04359-
dc.contributor.localIdA02315-
dc.relation.journalcodeJ00516-
dc.identifier.eissn1520-5002-
dc.identifier.urlhttp://pubs.acs.org/doi/abs/10.1021/cm070495s-
dc.contributor.alternativeNameSuh, Jin Suck-
dc.contributor.alternativeNameYang, Jae Moon-
dc.contributor.alternativeNameYoon, Ho Geun-
dc.contributor.alternativeNameHuh, Yong Min-
dc.contributor.affiliatedAuthorSuh, Jin Suck-
dc.contributor.affiliatedAuthorYoon, Ho Geun-
dc.contributor.affiliatedAuthorHuh, Yong Min-
dc.contributor.affiliatedAuthorYang, Jae Moon-
dc.rights.accessRightsnot free-
dc.citation.volume19-
dc.citation.startPage3870-
dc.citation.endPage3876-
dc.identifier.bibliographicCitationCHEMISTRY OF MATERIALS, Vol.19 : 3870-3876, 2007-
dc.identifier.rimsid53233-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
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