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A Case of Mediastinal and Pulmonary Cryptococcosis in a 3-Year-Old Immunocompetent Girl

Other Titles
 3세 면역정상 여아에서 발견된 종격동과 폐를 침범한 Cryptococcosis 1례 
 Hee Seon Lee ; Hyun Bin Park ; Sang Ho Cho ; Myung-Joon Kim ; Kyu-Earn Kim ; Myung Hyun Sohn ; Kyung Won Kim 
 Pediatric Allergy and Respiratory Disease (소아알레르기 호흡기학회지), Vol.21(4) : 350~355, 2011 
Journal Title
 Pediatric Allergy and Respiratory Disease  (소아알레르기 호흡기학회지) 
Issue Date
Cryptococcosis is an infrequently recognized infection in children, particularly those who are immunocompetent. The disease is mainly caused by Cryptococcus neoformans, a fungal pathogen that primarily affects the central nervous system (CNS) and lungs. Most reports of children with cryptococcosis are of the CNS or disseminated infections among immunocompromised patients. This report is a case of a 3-year-old immunocompetent girl who presented with intermittent fever and cough; a large mass was found in the right infrahilar area on chest X-ray. Chest computed tomography revealed large conglomerated mediastinal lymph nodes caused by C. neoformans, which was confirmed by the polymerase chain reaction as well as a histological evaluation. The patient improved after a prolonged period of antifungal therapy. This is the only known report of mediastinal and pulmonary cryptococcosis in an immunocompetent child
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1. 연구논문 > 1. College of Medicine > Dept. of Pediatrics
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
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