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Hepatocarcinogenesis: imaging-pathologic correlation

Authors
 Young Nyun Park  ;  Myeong-Jin Kim 
Citation
 ABDOMINAL IMAGING, Vol.36(3) : 232-243, 2011 
Journal Title
ABDOMINAL IMAGING
ISSN
 0942-8925 
Issue Date
2011
MeSH
Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/diagnostic imaging* ; Carcinoma, Hepatocellular/pathology* ; Humans ; Liver Cirrhosis/complications* ; Liver Neoplasms/complications ; Liver Neoplasms/diagnostic imaging* ; Liver Neoplasms/pathology* ; Tomography, X-Ray Computed
Keywords
Hepatocellular carcinoma ; Pathology ; Computed tomography ; Magnetic resonance imaging ; Diagnosis ; Borderline lesion
Abstract
Rapid advances in liver surgery, including liver transplantation, radiology, and pathology, have created a need for clinically relevant nomenclature for premalignant and early lesions of hepatocellular carcinoma (HCC). Precancerous lesions include dysplastic foci and dysplastic nodules (DNs) characterized by cytologic or structural atypia. Although imaging diagnosis is playing a crucial role in the evaluation of hepatocarcinogenesis and early diagnosis of HCC, it is still challenging to accurately characterize borderline nodules such as small arterially enhancing lesions or hypovascular nodules. This article discusses pathological and radiological features of these small nodular lesions and offers insights into the multistep process of hepatocarcinogenesis by describing the progression of pathologic change linking DNs to HCC.
Full Text
http://link.springer.com/article/10.1007%2Fs00261-011-9688-y
DOI
10.1007/s00261-011-9688-y
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Park, Young Nyun(박영년) ORCID logo https://orcid.org/0000-0003-0357-7967
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94184
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