Cited 48 times in
Cardiac magnetic resonance imaging-derived pulmonary artery distensibility index correlates with pulmonary artery stiffness and predicts functional capacity in patients with pulmonary arterial hypertension
DC Field | Value | Language |
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dc.contributor.author | 강기운 | - |
dc.contributor.author | 심지영 | - |
dc.contributor.author | 양우인 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 장혁재 | - |
dc.contributor.author | 정남식 | - |
dc.contributor.author | 최병욱 | - |
dc.contributor.author | 하종원 | - |
dc.date.accessioned | 2014-12-20T17:02:28Z | - |
dc.date.available | 2014-12-20T17:02:28Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1346-9843 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93849 | - |
dc.description.abstract | BACKGROUND: Increased stiffness of the pulmonary vascular bed is known to increase mortality in patients with pulmonary arterial hypertension (PAH); and pulmonary artery (PA) stiffness is also thought to be associated with exercise capacity. The purpose of the present study was to investigate whether cardiac magnetic resonance imaging (CMRI)-derived PA distensibility index correlates with PA stiffness estimated on right heart catheterization (RHC) and predicts functional capacity (FC) in patients with PAH. METHODS AND RESULTS: Thirty-five consecutive PAH patients (23% male, mean age, 44 ± 13 years; 69% idiopathic) underwent CMRI, RHC, and 6-min walk test (6MWT). PA distensibility indices were derived from cross-sectional area change (%) in the transverse view, perpendicular to the axis of the main PA, on CMRI [(maximum area-minimum area)/minimum area during cardiac cycle]. Among the PA stiffness indices, pulmonary vascular resistance (PVR) and PA capacitance were calculated using hemodynamic dataset from RHC. CMRI-derived PA distensibility was inversely correlated with PVR (R²=0.34, P<0.001) and directly correlated with PA capacitance (R²=0.35, P<0.001), and the distance in the 6MWT (R²=0.61, P<0.001). Furthermore, PA distensibility <20% predicted poor FC (<400m in 6MWT) with a sensitivity of 82% and a specificity of 94%. CONCLUSIONS: Non-invasive CMRI-derived PA distensibility index correlates with PA stiffness and can predict FC in patients with PAH. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 2244~2251 | - |
dc.relation.isPartOf | CIRCULATION JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Cardiac Catheterization | - |
dc.subject.MESH | Familial Primary Pulmonary Hypertension | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension, Pulmonary/diagnostic imaging* | - |
dc.subject.MESH | Hypertension, Pulmonary/physiopathology* | - |
dc.subject.MESH | Magnetic Resonance Angiography/methods* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pulmonary Artery/diagnostic imaging* | - |
dc.subject.MESH | Pulmonary Artery/physiopathology* | - |
dc.subject.MESH | Radiography | - |
dc.subject.MESH | Vascular Resistance* | - |
dc.title | Cardiac magnetic resonance imaging-derived pulmonary artery distensibility index correlates with pulmonary artery stiffness and predicts functional capacity in patients with pulmonary arterial hypertension | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Ki-Woon Kang | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Young-Jin Kim | - |
dc.contributor.googleauthor | Byoung-Wook Choi | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Woo-In Yang | - |
dc.contributor.googleauthor | Chi-Young Shim | - |
dc.contributor.googleauthor | Jongwon Ha | - |
dc.contributor.googleauthor | Namsik Chung | - |
dc.identifier.doi | 10.1253/circj.CJ-10-1310 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00007 | - |
dc.contributor.localId | A02213 | - |
dc.contributor.localId | A02301 | - |
dc.contributor.localId | A03490 | - |
dc.contributor.localId | A03585 | - |
dc.contributor.localId | A04059 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J00534 | - |
dc.identifier.eissn | 1347-4820 | - |
dc.identifier.pmid | 21757816 | - |
dc.contributor.alternativeName | Kang, Ki Woon | - |
dc.contributor.alternativeName | Shim, Chi Young | - |
dc.contributor.alternativeName | Yang, Woo In | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.alternativeName | Chung, Nam Sik | - |
dc.contributor.alternativeName | Choi, Byoung Wook | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Kang, Ki Woon | - |
dc.contributor.affiliatedAuthor | Shim, Chi Young | - |
dc.contributor.affiliatedAuthor | Yang, Woo In | - |
dc.contributor.affiliatedAuthor | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | Chung, Nam Sik | - |
dc.contributor.affiliatedAuthor | Choi, Byoung Wook | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 75 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2244 | - |
dc.citation.endPage | 2251 | - |
dc.identifier.bibliographicCitation | CIRCULATION JOURNAL, Vol.75(9) : 2244-2251, 2011 | - |
dc.identifier.rimsid | 28506 | - |
dc.type.rims | ART | - |
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