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Treatment outcomes of juvenile nasopharyngeal angiofibroma according to surgical approach.

 Dong-Woo Hyun  ;  Ji-Hwan Ryu  ;  Yoo-Suk Kim  ;  Kyu-Bo Kim  ;  Won Shik Kim  ;  Chang-Hoon Kim  ;  Joo-Heon Yoon 
 International Journal of Pediatric Otorhinolaryngology, Vol.75(1) : 69-73, 2011 
Journal Title
 International Journal of Pediatric Otorhinolaryngology 
Issue Date
OBJECTIVE: This is a retrospective study to assess treatment outcomes according to stage and surgical approach in advanced juvenile nasopharyngeal angiofibroma (JNA). METHODS: We retrospectively evaluated 20 JNA patients diagnosed and treated at our hospital. We only enrolled advanced disease with Radkowski stages greater than I and with minimum follow-up of 1 year (range 1-8.5). RESULTS: Recurrence or remnants were observed in 7 patients out of 20 patients (35.0%) who underwent primary surgical resection of advanced JNA and the mean interval to recurrence was 15.6 months (range 6-38). A recurrence rate according to a different stage was as follows: 33.3% in stage IIa, 33.3% in stage IIb, 50.0% in stage IIc and no recurrence in stage III. An endoscopic approach was chosen in 4 patients among these patients, four were classified as stage IIb tumors, one as a stage IIc tumor, with a recurrence rate of 25.0%, but no recurrence found in stage IIa disease. A midfacial degloving approach was used in 7 patients, with a recurrence rate of 42.9% and maxillary swing approach was taken in 3 patients with complete control. Postoperative complications required interventions occurred in 14.8%, more in the invasive maxillary swing or infratemporal fossa approaches. CONCLUSIONS: Although selecting minimal invasive or invasive approaches is equivocal, we recommend using the endoscopic approach or a midfacial degloving approach for the treatment of JNA extended to the pterygopalatine fossa. For stage III, aggressive surgery is preferable to guaranty a complete resection even if postoperative complications are more frequent. For a stage IIc, we could choose between a minimally invasive approach or a more aggressive one balancing between the possibility of salvage surgery in the future and the occurrence of postoperative healing problems
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Otorhinolaryngology (이비인후과학교실)
1. Journal Papers (연구논문) > 5. Research Institutes (연구소) > Research Center for Human Natural Defense System (생체방어연구센터)
Yonsei Authors
김원식(Kim, Won Shik)
김유석(Kim, Yoo Suk)
김창훈(Kim, Chang Hoon)
유지환(Ryu, Ji Hwan)
윤주헌(Yoon, Joo Heon)
현동우(Hyun, Dong Woo)
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