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Is confrontation naming performance in Alzheimer's disease the nominal linguistic retrogenesis of normal development?

 Kim H. ; Yoon J.H. ; Na D.L. ; Sohn Y.H. ; Baek E.J. ; Lee J.E. 
 European Neurology, Vol.66(4) : 195~199, 2011 
Journal Title
 European Neurology 
Issue Date
We investigated confrontation naming performance of patients with Alzheimer's disease (AD) and normal children (NC) to see if the nature of naming performance of AD patients is the reversal of that in normal development. Sixty items of the Boston Naming Test were given to 78 AD patients (and 40 age- and education-matched normal elderly) and 1,080 NC (3- to 14-year-olds). The analyses revealed that, firstly, the naming abilities of the AD patients demonstrated an inverse relationship with those of the NC. Secondly, from the clinical point of view, AD patients tended to lose vocabulary acquired later first while maintaining those acquired in earlier stages of development. Based on the findings, we claimed that this phenomenon was 'a nominal retrogenesis' in which 'retrogenesis' is 'the process by which degenerative mechanisms reverse the order of acquisition in normal development' as defined by Reisberg and colleagues.
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1. 연구논문 > 1. College of Medicine > Dept. of Rehabilitation Medicine
1. 연구논문 > 1. College of Medicine > Dept. of Neurology
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