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Detection of small intrahepatic metastases of hepatocellular carcinomas using diffusion-weighted imaging: comparison with conventional dynamic MRI.

Authors
 Eun-Suk Cho ; Jeong-Sik Yu ; Dae Jung Kim ; Ki Whang Kim ; Jhii-Hyun Ahn ; Joo Hee Kim ; Jae-Joon Chung 
Citation
 Magnetic Resonance Imaging, Vol.29(7) : 985~992, 2011 
Journal Title
 Magnetic Resonance Imaging 
ISSN
 0730-725X 
Issue Date
2011
Abstract
PURPOSE: The purpose of our study was to compare diffusion-weighted MR imaging (DWI) with conventional dynamic MRI in terms of the assessment of small intrahepatic metastases from hepatocellular carcinoma (HCC). MATERIALS AND METHODS: In 24 patients with multifocal, small (≤2 cm) intrahepatic metastatic foci of advanced HCC, a total of 134 lesions (≤1 cm, n=81; >1 cm, n=53) were subjected to a comparative analysis of hepatic MRI including static and gadopentetate dimeglumine-enhanced dynamic imaging, and DWI using a single-shot spin-echo echo-planar MRI (b values=50, 400 and 800 s/mm(2)), by two independent reviewers. RESULTS: A larger number of the lesions were detected and diagnosed as intrahepatic metastases on DWI [Reviewer 1, 121 (90%); Reviewer 2, 117 (87%)] than on dynamic imaging [Reviewer 1, 107 (80%); Reviewer 2, 105 (78%)] (P<.05). For the 81 smaller lesions (≤1 cm), DWI was able to detect more lesions than dynamic imaging [Reviewer 1, 68 (84%) vs. 56 (69%), P=.008; Reviewer 2, 65 (80%) vs. 55 (68%), P=.031], but there was no statistically significant difference between the two image sets for larger (>1 cm) lesions. CONCLUSION: Due to its higher detection rate of subcentimeter lesions, DWI could be considered complementary to dynamic MRI in the diagnosis of intrahepatic metastases of HCCs.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/93599
DOI
10.1016/j.mri.2011.04.010
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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Link
 http://www.sciencedirect.com/science/article/pii/S0730725X11001408
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