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Gadoxetate disodium-enhanced magnetic resonance imaging versus contrast-enhanced 18F-fluorodeoxyglucose positron emission tomography/computed tomography for the detection of colorectal liver metastases
DC Field | Value | Language |
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dc.contributor.author | 김명진 | - |
dc.contributor.author | 라선영 | - |
dc.contributor.author | 박영년 | - |
dc.contributor.author | 유선국 | - |
dc.contributor.author | 최진영 | - |
dc.date.accessioned | 2014-12-20T16:49:26Z | - |
dc.date.available | 2014-12-20T16:49:26Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0020-9996 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93446 | - |
dc.description.abstract | PURPOSE: : To compare the diagnostic accuracy of gadoxetate disodium-enhanced magnetic resonance imaging (EOB-MRI) on a 3-T system and integrated contrast-enhanced F-fluorodeoxyglucose positron emission tomography/computed tomography (CE-PET/CT) for the detection of hepatic metastases from colorectal cancers. MATERIALS AND METHODS: : The approval from the institutional review board was obtained, and the requirement for informed consent was waived. We retrospectively evaluated 135 metastases in 68 patients (37 men, 31 women; mean age: 68 years; age range: 37-82 years) who underwent both EOB-MRI and CE-PET/CT. A total of 103 metastases were confirmed during surgery and 32 were confirmed by imaging findings during follow-up. The images were independently reviewed by 2 observers. The diagnostic accuracies of EOB-MRI and CE-PET/CT were determined by calculating the areas under each reader-specific receiver operating characteristic curve (Az). Patient-based lesion sensitivity and specificity were compared using the McNemar test. RESULTS: : The mean area under the Az on EOB-MRI versus CE-PET/CT was 0.94 versus 0.81 for all lesions (P < 0.001), 0.92 versus 0.60 for lesions ≤1 cm in size (P < 0.001), and 0.88 versus 0.96 for lesions >1 cm (P = 0.098), respectively. The sensitivity, specificity, positive predictive values, and negative predictive value on a patient basis were 100%, 71%, 97%, and 100% for EOB-MRI and 93%, 71%, 97%, and 57% for CE-PET/CT, respectively. CONCLUSIONS: : EOB-MRI using a 3-T system is more accurate than CE-PET/CT, especially for the detection of small (≤1.0 cm) lesions. Patient-based analysis revealed that EOB-MRI has a higher sensitivity and negative predictive value than CE-PET/CT. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 548~555 | - |
dc.relation.isPartOf | INVESTIGATIVE RADIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Colorectal Neoplasms/diagnosis* | - |
dc.subject.MESH | Colorectal Neoplasms/pathology | - |
dc.subject.MESH | Contrast Media* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorodeoxyglucose F18 | - |
dc.subject.MESH | Gadolinium DTPA* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Neoplasms/diagnosis* | - |
dc.subject.MESH | Liver Neoplasms/secondary | - |
dc.subject.MESH | Magnetic Resonance Imaging/instrumentation* | - |
dc.subject.MESH | Magnetic Resonance Imaging/methods | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Positron-Emission Tomography/instrumentation* | - |
dc.subject.MESH | Positron-Emission Tomography/methods | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Radiopharmaceuticals | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Statistics as Topic | - |
dc.subject.MESH | Tomography, X-Ray Computed/instrumentation | - |
dc.subject.MESH | Tomography, X-Ray Computed/methods | - |
dc.title | Gadoxetate disodium-enhanced magnetic resonance imaging versus contrast-enhanced 18F-fluorodeoxyglucose positron emission tomography/computed tomography for the detection of colorectal liver metastases | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiology (영상의학) | - |
dc.contributor.googleauthor | Hyo Jung Seo | - |
dc.contributor.googleauthor | Myeong-Jin Kim | - |
dc.contributor.googleauthor | Jong Doo Lee | - |
dc.contributor.googleauthor | Woo-Suk Chung | - |
dc.contributor.googleauthor | Yeo-Eun Kim | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00426 | - |
dc.contributor.localId | A02471 | - |
dc.contributor.localId | A04200 | - |
dc.contributor.localId | A01316 | - |
dc.relation.journalcode | J01188 | - |
dc.identifier.eissn | 1536-0210 | - |
dc.identifier.pmid | 21577131 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004424-201109000-00003&LSLINK=80&D=ovft | - |
dc.subject.keyword | liver | - |
dc.subject.keyword | metastases | - |
dc.subject.keyword | gadoxetate disodium-enhanced MRI | - |
dc.subject.keyword | contrast-enhanced PET/CT | - |
dc.contributor.alternativeName | Kim, Myeong Jin | - |
dc.contributor.alternativeName | Rha, Sun Young | - |
dc.contributor.alternativeName | Park, Young Nyun | - |
dc.contributor.alternativeName | Yoo, Sun Kook | - |
dc.contributor.alternativeName | Choi, Jin Young | - |
dc.contributor.affiliatedAuthor | Kim, Myeong Jin | - |
dc.contributor.affiliatedAuthor | Yoo, Sun Kook | - |
dc.contributor.affiliatedAuthor | Choi, Jin Young | - |
dc.contributor.affiliatedAuthor | Rha, Sun Young | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 46 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 548 | - |
dc.citation.endPage | 555 | - |
dc.identifier.bibliographicCitation | INVESTIGATIVE RADIOLOGY, Vol.46(9) : 548-555, 2011 | - |
dc.identifier.rimsid | 28240 | - |
dc.type.rims | ART | - |
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