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Low-dose coronary computed tomography angiography using prospective ECG-triggering compared to invasive coronary angiography

Authors
 Yoo Jin Hong  ;  Sang Jin Kim  ;  Sang Min Lee  ;  Phil Ki Min  ;  Young Won Yoon  ;  Byung Kwon Lee  ;  Tae Hoon Kim 
Citation
 INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol.27(3) : 425-431, 2011 
Journal Title
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
ISSN
 1569-5794 
Issue Date
2011
MeSH
Aged ; Artifacts ; Calcinosis/diagnostic imaging ; Calcinosis/physiopathology ; Cardiac-Gated Imaging Techniques* ; Coronary Angiography/methods* ; Coronary Stenosis/diagnostic imaging* ; Coronary Stenosis/physiopathology ; Electrocardiography* ; False Negative Reactions ; False Positive Reactions ; Female ; Heart Rate ; Humans ; Male ; Middle Aged ; Observer Variation ; Predictive Value of Tests ; Prospective Studies ; Radiation Dosage* ; Reproducibility of Results ; Republic of Korea ; Severity of Illness Index ; Tomography, X-Ray Computed*
Keywords
Prospectively ECG-triggering 64-slice MDCT coronary angiography ; Coronary artery disease ; Coronary angiography
Abstract
To assess the diagnostic accuracy of prospective ECG-triggering 64-slice multidetector computed tomography (MDCT) coronary angiography for evaluation of coronary artery disease (CAD). Forty-two patients (31 males, 11 females, mean age 64 years) underwent cardiac CT and invasive coronary angiography (ICA). Patients with a heart rate of <65 beats/min with stable heart rhythm were included in the study sample. We used a prospective ECG-triggering protocol. Luminal narrowing over 50% was considered to be significant according to a modified 17-segment AHA model, using invasive coronary angiography (ICA) as the standard of reference. The mean radiation dose was 3.5 mSv ± 0.3 (range, 3.3-4.2 mSv), and 542 of 549 segments (98.7%) in the 42 patients were diagnostic. In contrast, 119 of 542 segments (22%) were diagnosed as significant by ICA. The sensitivity, specificity, accuracy, PPV and NPV were 95.0, 96.2, 96, 85.8 and 98.8%, respectively. False positive results were affected by densely calcified plaques, whereas false negatives were caused by motion artifact with poor vessel attenuation at the distal segments or near the bifurcation area of the coronary arteries. Prospective ECG-triggering MDCT is a useful method for evaluating CAD in patients with a lower heart rate with low radiation dose.
Full Text
http://link.springer.com/article/10.1007%2Fs10554-010-9674-4
DOI
10.1007/s10554-010-9674-4
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sang Jin(김상진)
Kim, Tae Hoon(김태훈) ORCID logo https://orcid.org/0000-0003-3598-2529
Min, Pil Ki(민필기) ORCID logo https://orcid.org/0000-0001-7033-7651
Yoon, Young Won(윤영원) ORCID logo https://orcid.org/0000-0002-0907-0350
Lee, Byoung Kwon(이병권) ORCID logo https://orcid.org/0000-0001-9259-2776
Lee, Sang Min(이상민)
Hong, Yoo Jin(홍유진) ORCID logo https://orcid.org/0000-0002-7276-0944
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/93292
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