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Focal eosinophilic infiltration of the liver: gadoxetic acid-enhanced magnetic resonance imaging and diffusion-weighted imaging.

Authors
 Sung Jun Ahn  ;  Jin-Young Choi  ;  Kyung Ah Kim  ;  Myeong-Jin Kim  ;  Song-Ee Baek  ;  Joo Hee Kim  ;  Ho-Taek Song 
Citation
 JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, Vol.35(1) : 81-85, 2011 
Journal Title
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY
ISSN
 0363-8715 
Issue Date
2011
MeSH
Aged ; Aged, 80 and over ; Contrast Media* ; Diffusion Magnetic Resonance Imaging ; Eosinophilia/diagnosis* ; Female ; Gadolinium DTPA* ; Humans ; Image Interpretation, Computer-Assisted ; Liver Diseases/diagnosis* ; Magnetic Resonance Imaging/methods* ; Male ; Middle Aged ; Retrospective Studies
Keywords
eosinophil l ; liver ; magnetic resonance imaging ; gadolinium-ethoxybenzyl-DTPA ; diffusion-weighted image
Abstract
OBJECTIVES: Using gadoxetic acid-enhanced magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI), the purpose of this study was to evaluate findings of focal hepatic eosinophilic infiltration.

METHODS: This retrospective study included 8 patients with 7 histologically confirmed focal eosinophilic infiltration (FEI) of the liver. One case was considered as FEI by using clinical findings and follow-up imaging. Gadoxetic acid-enhanced MRI and DWI were reviewed by 2 radiologists. We evaluated the signal intensity of focal lesions on T1-weighted, T2-weighted, and DW images and the pattern of enhancement in arterial, portal, equilibrium, and hepatobiliary phases of the gadoxetic acid-enhanced MRI. Apparent diffusion coefficient (ADC) value for focal eosinophilic infiltration was also calculated.

RESULTS: On T2-weighted images, 7 (88%) of 8 cases (7/8 lesions) showed mixed hyperintensity with irregular margins. Six (75%) of the 8 cases showed rim enhancement in the arterial phase. Most cases (5/8 lesions [63%]) showed isointensity or hypointensity in the portal and equilibrium phases. In the hepatobiliary phase, all cases (8/8) showed mixed hypointensity with irregular margins and nonspherical shapes. All cases showed hyperintensity in both low and high b-value ranges on DWI. The ADCs for 6 cases showed less than 1.05 × 10(-3) mm2/s (0.74 × 10(-3) to 1.03 × 10(-3) mm2/s).

CONCLUSIONS: Focal eosinophilic infiltration showed mixed hypointensity, irregular margins, and nonspherical shapes with excellent lesion-to-liver contrast in the hepatobiliary phase of the gadoxetic acid-enhanced MRI. Diffusion-weighted imaging and ADCs may not be helpful for characterizing these benign hepatic lesions.
Full Text
http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00004728-201101000-00016&D=ovft&PDF=y
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Myeong Jin(김명진) ORCID logo https://orcid.org/0000-0001-7949-5402
Kim, Joo Hee(김주희) ORCID logo https://orcid.org/0000-0001-5383-3602
Baek, Song Ee(백송이) ORCID logo https://orcid.org/0000-0001-8146-2570
Song, Ho Taek(송호택) ORCID logo https://orcid.org/0000-0002-6655-2575
Ahn, Sung Jun(안성준) ORCID logo https://orcid.org/0000-0003-0075-2432
Choi, Jin Young(최진영) ORCID logo https://orcid.org/0000-0002-9025-6274
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92925
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