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Subcategorization of ultrasonographic BI-RADS category 4: positive predictive value and clinical factors affecting it.

Authors
 Jung Hyun Yoon ; Min Jung Kim ; Eun-Kyung Kim ; Jin Young Kwak ; Hee Jung Moon 
Citation
 Ultrasound in Medicine and Biology, Vol.37(5) : 693~699, 2011 
Journal Title
 Ultrasound in Medicine and Biology 
ISSN
 0301-5629 
Issue Date
2011
Abstract
The objective of this study was to evaluate the positive predictive value (PPV) in ultrasonographically (US)-detected breast lesions of BI-RADS category 4a, 4b and 4c and to find how various clinical factors influenced the PPV of category 4. A total of 2142 women with 2430 breast lesions diagnosed on US as BI-RADS category 4 and underwent biopsy were included. Among them, 452 (18.6%) were pathologically confirmed as malignancy. PPV of each US BI-RADS subcategory was 7.6% (149/1963) for category 4a, 37.8% (68/180) for category 4b and 81.9% (235/287) for category 4c. Several clinical factors were more significantly seen in malignancy of category 4a and 4b, whereas none of the factors showed significance in category 4c. Subcategorization of category 4 is a feasible method in predicting malignancy in which patients' age, lack of multiplicity and symptoms affected the PPV of category 4 lesions.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/92831
DOI
10.1016/j.ultrasmedbio.2011.02.009
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Radiology
Yonsei Authors
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Link
 http://www.sciencedirect.com/science/article/pii/S0301562911001049
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