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고령 환자 골절에서 가골 생성 촉진을 위한 부갑상선 호르몬의 간헐적 투여

Other Titles
 Intermittent Parathyroid Hormone Treatment for Stimulation of Callus Formation in Elderly Patients. 
 송형근  ;  김성준  ;  이재후  ;  양규현 
 Journal of the Korean Fracture Society (대한골절학회지), Vol.25(4) : 295-299, 2012 
Journal Title
 Journal of the Korean Fracture Society (대한골절학회지) 
Issue Date
Fracture healing ; Parathyroid hormone
PURPOSE: The purpose of this study was to evaluate the effect of parathyroid hormone (PTH) on fracture healing in elderly patients. MATERIALS AND METHODS: We analyzed the radiologic results in 14 patients. Group I (n=7) was administrated intermittent PTH after surgical treatment and group II (n=7) was treated only with surgery. We checked the time of initial callus formation, bridging callus formation, and bone union through periodic follow-up radiographs by a radiologist who did not know the patient's information. RESULTS: The mean time to initial callus formation was 6 weeks for group I, compared with 6.7 weeks for group II. The mean time to bridging callus formation was 15.9 weeks for group I, compared with 23.0 weeks for group II. The mean time to bone union was 28.7 weeks for group I, compared with 41.9 weeks for group II. The difference in the cumulative detection rate (CDR) of the initial callus formation of group I and II was not statistically significant (p=0.793). However, the CDR of the bridging callus formation and bone union for group I were higher than those of group II (p=0.008, p=0.001, respectively). CONCLUSION: The intermittent PTH administration after surgical treatment and maximum possible preservation of the periosteum in elderly patients accelerates fracture healing.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sungjun(김성준) ORCID logo https://orcid.org/0000-0002-7876-7901
Yang, Kyu Hyun(양규현) ORCID logo https://orcid.org/0000-0001-7183-588X
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